819804-85-8

Upstream product

• 72155-45-4 Boc-L-phenylalaninal 
• 26480-92-2 3-Phenyl-2-triphenylphosphoranyliden-propionsaeuremethylester 

Downstream Products

• 852459-93-9 (3S,5R)-3,5-Dibenzyl-1-[(2S,4R)-4-(4-benzyloxy-benzyl)-5-((3aS,8aR)-2,2-dimethyl-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-yl)-2-hydroxy-5-oxo-pentyl]-pyrrolidin-2-one 
• 852460-12-9 {4-[(2R,4S)-5-((3S,5R)-3,5-Dibenzyl-2-oxo-pyrrolidin-1-yl)-4-hydroxy-2-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-pentyl]-phenoxy}-acetic acid methyl ester 
• 852460-16-3 {4-[(2R,4S)-5-((3S,5R)-3,5-Dibenzyl-2-oxo-pyrrolidin-1-yl)-4-hydroxy-2-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-pentyl]-phenoxy}-acetic acid 
• 194655-89-5 (3S,5R)-3,5-Dibenzyl-pyrrolidin-2-one 
• 194599-07-0 2-benzyl-4-tert-butoxycarbonylamino-5-phenyl-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Optimization of pyrrolidinone based HIV protease inhibitors

The synthesis and enhanced antiviral activity of a series of P1′-optimized 3,5-dibenzyl pyrrolidinone based HIV protease inhibitors is described. Optimization of P1-substituted pyrrolidinone based HIV protease inhibitors has yielded analogs with very pote