819850-13-0

Basic information

• Product Name: (1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: 1H-INDOL-4-YL-CARBAMIC ACID, 1,1-DIMETHYLETHYL ESTER;(1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER;N-BOC-4-aMinoindole;tert-butyl N-(1H-indol-4-yl)carbamate
• CAS NO: 819850-13-0
• Molecular Formula: C₁₃H₁₆N₂O₂
• Molecular Weight: 232.28
• Mol File: 819850-13-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 350.4°C at 760 mmHg
• Flash Point: 165.7°C
• Appearance: /
• Density: 1.216
• Vapor Pressure: 4.42E-05mmHg at 25°C
• Refractive Index: 1.635
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: (1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER(819850-13-0)
• EPA Substance Registry System: (1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER(819850-13-0)

Safety Data

• Hazardous Substances Data: 819850-13-0(Hazardous Substances Data)

Usage

General Description

"(1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER" is a chemical compound with the molecular formula C14H18N2O2. It is a tert-butyl ester derivative of indole-4-carbamic acid and is commonly used in organic synthesis and pharmaceutical research. (1H-INDOL-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER has potential applications in the development of new drugs and as a building block for the synthesis of various biologically active compounds. It is important to handle and store this chemical with care, following the proper safety protocols and guidelines to avoid any potential hazards.

InChI:InChI=1/C13H16N2O2/c1-13(2,3)17-12(16)15-11-6-4-5-10-9(11)7-8-14-10/h4-8,14H,1-3H3,(H,15,16)

Upstream product

• 1380445-23-7 tert-butyl N-(7-bromo-1H-indol-4-yl)carbamate 
• 73183-34-3 bis(pinacol)diborane 
• 1380445-22-6 (4-bromo-3-nitrophenyl)carbamic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 53324-38-2 4-bromo-3-nitroaniline 
• 5192-23-4 4-amino-1H-indole 

Relevant articles and documents

Small molecule compound

The invention provides a small molecular compound, The small molecular compound is characterized by having a structure as shown in the following molecular general formula, wherein X1 and X2 are selected from carbon or nitrogen, G1 is a carbon ring or a heterocyclic ring with aromaticity, any one or more hydrogen atoms on the G1 ring are substituted by R1, wherein R1 is selected from nitrogen-containing groups. The small molecule compound can be used as an efficient and specific JAK kinase inhibitor, especially a Tyk2 inhibitor, and/or a JAK1 inhibitor, and/or a JAK1/Tyk2 dual inhibitor, or a Tyk2/JAK1 dual inhibitor or a Tyk2/Jak2 dual inhibitor.

AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Provided herein are aromatic heterocyclic derivatives or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof used for treating Alzheimer's disease. Also provided herein are pharmaceutica