82087-52-3Relevant academic research and scientific papers
Aryloxy cyclohexyl imidazoles: A novel class of antileishmanial agents
Srinivas, Nagarapu,Palne, Shraddha,Nishi,Gupta, Suman,Bhandari, Kalpana
scheme or table, p. 324 - 327 (2011/02/28)
Thirteen novel aryloxy cyclohexane-based mono and bis imidazoles were synthesized and evaluated in vitro as antileishmanials against Leishmania donovani and cytotoxicity assessed. These compounds were better than the existing drugs, sodium stibogluconate
Carbon-Carbon Bond Formation by the Use of Chloroiodomethane as a C1 Unit. IV. The Mannich Reaction of Ketones by Means of Dihalomethane and Secondary Amine
Miyano, Sotaro,Mori, Akira,Hokari, Hiroshi,Ohta, Katsuaki,Hashimoto, Harukichi
, p. 1331 - 1332 (2007/10/02)
Treatment of ketones with dihalomethane (CH2Br2, CH2ClI, and CH2I2) in the presence of secondary amine, preferably pyrrolidine, gave the corresponding Mannich base in varing yields depending on the substrate and/or combination of the reagents.
