82117-98-4

Upstream product

• 100-63-0 phenylhydrazine 
• 10191-60-3 dimethyl N-cyanodithioiminocarbonate 
• 73491-54-0 Nitroguanyl-imido-dithiokohlensaeuredimethylester 

Downstream Products

• 132395-56-3 C₂₄H₂₂N₄S₃ 
• 132395-52-9 Dimethyl (3-methylthio-1-phenyl-1H-1,2,4-triazol-5-yl)iminodithiocarbonate 
• 132395-74-5 1,3-Bis(3-methylthio-1-phenyl-1H-1,2,4-triazol-5-yl)2-methyl-isothiourea 
• 84828-23-9 5-benzalimino-3-methylthio-1-phenyl-1H-1,2,4-triazole 
• 84828-26-2 (5-Methylsulfanyl-2-phenyl-2H-[1,2,4]triazol-3-yl)-[1-(3,4,5-trimethoxy-phenyl)-meth-(Z)-ylidene]-amine 
• 84828-25-1 [1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-(5-methylsulfanyl-2-phenyl-2H-[1,2,4]triazol-3-yl)-amine 

Relevant academic research and scientific papers

Synthesis of Substituted 5-Amino-1,2,4-triazoles

N-Nitro-amidino-dithiocarbimidic acid dimethylester 1 reacts with monosubstituted hydrazines under formation of the substituted 5-amino-1,2,4-triazoles.Disubstituted hydrazines give under the same conditions N-nitro-amidino-S-methyl-isothiosemicarbazides.The reaction of some more hydrazine derivatives with 1 yields the adequate substituted 1,2,4-triazoles.

On Triazoles. I. The reaction of N-Cyanocarbonimidodithioic Acid Diesters With Hydrazines

The reaction of N-cyanocarbonimidodithioic acid di(alkyl and aralkyl)esters with different alkyl-, aralkyl- and aryl hydrazines to yield 1-substituted-3-R-thio-5-amino-1H-1,2,4-triazoles (3) and 2-substituted-3-R-thio-5-amino-2H-1,2,4-triazoles (4) was studied.Isolation of the different types of isomeric pairs of 3 and 4 helped to prove the structure of products obtained which made possible correction of some confusion in the literature.The 3 (R = H) tautomeric structure of the non-substituted derivatives was supported by comparison of their uv and cmr spectra with those of the alkylated and aralkylated derivatives 3 and 4, respectively, again correcting confusion in literature.An hplc determination of the ratio of products 3 and 4 formed in the above reactions with different hydrazines made it possible to prove the mechanism of the reaction.