82131-05-3

Basic information

• Product Name: (4-Iodobutyl) Pivalate
• Synonyms: (4-Iodobutyl) Pivalate
• CAS NO: 82131-05-3
• Molecular Formula: C₉H₁₇IO₂
• Molecular Weight: 284
• Mol File: 82131-05-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 262.025°C at 760 mmHg
• Flash Point: 112.269°C
• Appearance: /
• Density: 1.425g/cm³
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: (4-Iodobutyl) Pivalate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Iodobutyl) Pivalate(82131-05-3)
• EPA Substance Registry System: (4-Iodobutyl) Pivalate(82131-05-3)

Safety Data

• Hazardous Substances Data: 82131-05-3(Hazardous Substances Data)

Usage

General Description

(4-Iodobutyl) Pivalate is a chemical compound composed of a butyl group that is substituted with an iodine atom and a pivaloyloxy group. It is often used as a reagent and intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and agrochemical industries. (4-Iodobutyl) Pivalate can also be utilized as a building block for the production of specialized polymers and materials. It is important to handle this compound with caution, as it may pose hazards to human health and the environment if not properly managed.

InChI:InChI=1/C9H17IO2/c1-9(2,3)8(11)12-7-5-4-6-10/h4-7H2,1-3H3

Upstream product

• 109-99-9 tetrahydrofuran 
• 3282-30-2 pivaloyl chloride 
• 61915-52-4 2,2-Dimethylpropanoyl iodide 
• 209254-60-4 4-pivaloyloxy-1-butanol 
• 169396-64-9 2,2-Dimethyl-propionic acid 4-(toluene-4-sulfonyloxy)-butyl ester 

Downstream Products

• 797032-02-1 2,2-dimethyl-propionic acid-4-(2-hydroxymethylbenzoimidazol-1-yl)butyl ester 
• 212514-40-4 2,2-Dimethyl-propionic acid (S)-7-ethoxycarbonylamino-6-oxo-5-(toluene-4-sulfonyl)-octyl ester 

Relevant articles and documents

Synthesis of n-alkyl terminal halohydrin esters from acid halides and cyclic ethers or thioethers under solvent- and catalyst-free conditions

An efficient and eco-friendly protocol has been developed for the preparation of n-alkyl terminal halohydrin esters under solvent- and catalyst-free conditions. Ring opening of cyclic ethers by organic acid halides affords the 1,4- and 1,5-halohydrins, OH-protected by different acyl groups. The green reaction conditions, simple work-up procedures, high yields and broad substrate scope of the reaction highlight the positive features of this method. This journal is

New coupling reactions of some acyl chlorides with samarium diiodide in the presence of samarium: Carbinols from three acyl units

A mixture of samarium(II) iodide and samarium can induce a coupling reaction of three molecules of alkanoyl halide to give trialkylcarbinols of 2-hydroxy-1,3-diones. When aliphatic, unbranched alkanoyl chlorides are used, this new coupling reaction provides trimeric products as the main reaction products. Tetrahydropyran (THP) proved superior as the solvent because no ring-opening and subsequent reaction with the alkanoyl halides was observed under the reaction conditions, unlike when THF was used. Wiley-VCH Verlag GmbH, 2000.

Synthesis of α-Hydroxy Ketones by Samarium(II) Iodide-Mediated Coupling of Organic Halides, an Isocyanide, and Carbonyl Compounds

A new strategy for the synthesis of α-hydroxy ketones by samarium(II) iodide-mediated three-component coupling of organic halides, an isocyanide, and carbonyl compounds is disclosed.An (α-iminoalkyl)samarium(III) species is generated in situ by treatment