114078-88-5

Basic information

• Product Name: 5-BroMo-1,2,3-triazine
• Synonyms: 5-BroMo-1,2,3-triazine
• CAS NO: 114078-88-5
• Molecular Formula: C₃H₂BrN₃
• Molecular Weight: 159.97208
• Mol File: 114078-88-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 112 °C (decomp)(Solv: ethyl acetate (141-78-6))
• Boiling Point: 242.531 °C at 760 mmHg
• Flash Point: 100.48 °C
• Appearance: /
• Density: 1.876 g/cm³
• Vapor Pressure: 0.053mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -1.31±0.10(Predicted)
• CAS DataBase Reference: 5-BroMo-1,2,3-triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-1,2,3-triazine(114078-88-5)
• EPA Substance Registry System: 5-BroMo-1,2,3-triazine(114078-88-5)

Safety Data

• Hazardous Substances Data: 114078-88-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-1,2,3-triazine is a chemical compound with the molecular formula C3H2BrN3. It is a heterocyclic compound that contains both nitrogen and bromine atoms. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It can also be used as a reagent in organic chemistry reactions. 5-Bromo-1,2,3-triazine is known for its versatility and is widely used in various chemical processes due to its ability to participate in a wide range of transformations.

InChI:InChI=1/C3H2BrN3/c4-3-1-5-7-6-2-3/h1-2H

Upstream product

• 2075-45-8 4-bromo-1H-pyrazole 
• 3994-46-5 N-aminopyrazole 
• 122481-11-2 4-bromo-1-trityl-1H-pyrazole 

Downstream Products

• 433226-06-3 2-amino-5-bromonicotinic acid ethyl ester 
• 947249-12-9 5-bromo-3-(3-(trifluoromethyl)phenyl)pyridin-2-amine 
• 1216771-35-5 methyl 4-(2-amino-5-bromopyridin-3-yl)benzoate 
• 709652-82-4 2-amino-5-bromonicotinonitrile 
• 38696-20-7 2-phenyl-5-bromopyrimidine 
• 1220038-46-9 5-bromo-2-diethylamino-3-methylpyridine 
• 7752-78-5 5-bromo-2-methylpyrimidine 
• 55849-30-4 5-bromo-2-ethoxypyridine 
• 82132-68-1 3-bromo-5,6,7,8-tetrahydroquinoline 
• 158331-18-1 3-bromo-6,7-dihydro-5H-cyclopenta[b]pyridine 

Relevant articles and documents

Access to pyridines via cascade nucleophilic addition reaction of 1,2,3-triazines with activated ketones or acetonitriles

We studied the cascade nucleophilic addition reactions of 1,2,3-triazines with activated acetonitriles or ketones, which were used to construct highly substituted pyridines that are not easily accessed by conventional methods. The strategy addressed some structural diversity issues currently facing medicinal chemistry, and the resulting pyridines could be used as convenient precursors for the synthesis of related pharmaceuticals. In particular, our method was applied to the syntheses of the marketed drug etoricoxib and several biologically important molecules in a few steps.

NOVEL TETRAHYDROISOQUINOLINES AND TERAHYDRONAPHTHYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The present invention provides novel compounds having the general formula (I): wherein R1, R 2, R 3, U, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.

Cyclic gyrase and topoisomerase IV inhibitor

The invention belongs to the technical field of medicament, and particularly relates to a compound shown in formula (I) (please see the formula (I) in the description), and acceptable salt, ester or stereoisomer of the compound in pharmacy. R1, R2, a ring