82145-80-0Relevant academic research and scientific papers
Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors
Paquin, Isabelle,Raeppel, Stephane,Leit, Silvana,Gaudette, Frederic,Zhou, Nancy,Moradei, Oscar,Saavedra, Oscar,Bernstein, Naomy,Raeppel, Franck,Bouchain, Giliane,Frechette, Sylvie,Woo, Soon H.,Vaisburg, Arkadii,Fournel, Marielle,Kalita, Ann,Robert, Marie-France,Lu, Aihua,Trachy-Bourget, Marie-Claude,Yan, Pu Theresa,Liu, Jianhong,Rahil, Jubrail,MacLeod, A. Robert,Besterman, Jeffrey M.,Li, Zuomei,Delorme, Daniel
, p. 1067 - 1071 (2008/09/18)
Inhibition of histone deacetylases (HDAC) is emerging as a new strategy in human cancer therapy. The synthesis and biological evaluation of a variety of 4-(heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides is presented herein. From the different series
Hypoglycemic 4-(((1,3,4, thiadiazolyl)thio)methyl)benzoic acids, ester and amides
-
, (2008/06/13)
4-(((Heterocyclo)thio)methyl)benzoic acids, esters, amides and pharmaceutically-acceptable salts thereof having hypoglycemic activity in mammals, including a method of use and pharmaceutically-acceptable compositions.
