821785-90-4Relevant academic research and scientific papers
First stereoselective total synthesis of (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran- 2-one
Radha Krishna, Palakodety,Srinivas, Ravula
, p. 2013 - 2015 (2007/10/03)
A stereoselective total synthesis of (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran- 2-one is reported. The strategy utilizes an iterative Jacobsen hydrolytic kinetic resolution, ring opening with a chiral propargylic synthon and
Biology-oriented synthesis of stereochemically diverse natural-product- derived compound collections by iterative allylations on a solid support
Umarye, Jayant D.,Lessmann, Torben,Garcia, Ana B.,Mamane, Victor,Sommer, Stefan,Waldmann, Herbert
, p. 3305 - 3319 (2008/02/10)
A strategy aiming at the introduction of stereocenters into polymer-bound natural-product-derived and -inspired compound collections is presented. Treatment of immobilized aldehydes with Brown's pinene-derived allylboranes results in the stereoselective f
The first stereoselective total synthesis of (6S)-5,6-dihydro-6-[(2R)-2- hydroxy-6-phenylhexyl]-2H-pyran-2-one
Chandrasekhar,Narsihmulu, Ch.,Sultana, S. Shameem,Srinivasa Reddy
, p. 9299 - 9301 (2007/10/03)
Iterative asymmetric allylations and ring-closing metathesis have been effectively performed for the first stereoselective total synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one, a novel α,β-unsaturated-δ-lactone having antifu
