821796-68-3

Basic information

• Product Name: Aziridine, 2-benzoyl-1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 821796-68-3
• Molecular Formula: C16H15NO3S
• Molecular Weight: 301.366
• Mol File: 821796-68-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Aziridine, 2-benzoyl-1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Aziridine, 2-benzoyl-1-[(4-methylphenyl)sulfonyl]-(821796-68-3)
• EPA Substance Registry System: Aziridine, 2-benzoyl-1-[(4-methylphenyl)sulfonyl]-(821796-68-3)

Safety Data

• Hazardous Substances Data: 821796-68-3(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 127-65-1 chloroamine-T 
• 768-03-6 Phenyl vinyl ketone 
• 6713-46-8 Benzoyl-2-aziridin 
• 98-59-9 p-toluenesulfonyl chloride 
• 101294-01-3 4-methyl-N-(3-oxo-3-phenyl-propyl)benzenesulfonamide 
• 936-59-4 3-chloropropiophenone 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 104504-02-1 4-methyl-N-(tosyloxy)benzenesulfonamide 

Downstream Products

• 585529-12-0 2-(1-phenylvinyl)-N-tosylaziridine 
• 939-23-1 p-phenylpyridine 

Relevant articles and documents

Aziridin-2-yl-(aryl) ketone derivative and preparation method thereof

The invention discloses an aziridin-2-yl-(aryl) ketone derivative and a preparation method thereof, and according to the preparation method, 3-aryl substituted propargyl alcohol, N-protected amine and N-halogenated succinimide are subjected to a multi-step cascade reaction to realize one-pot synthesis of the aziridin-2-yl-(aryl) ketone derivative. The yield of aziridin-2-yl-(aryl) ketone ranges from 70% to 90%, the method has the advantages of being easy to operate, mild in condition, high in yield and the like, and a brand-new synthesis method is provided for derivatives of aziridin-2-yl-(aryl) ketone.

Visible-Light Photoredox-Catalyzed Formal [5 + 1] Cycloaddition of N-Tosyl Vinylaziridines with Difluoroalkyl Halides

A visible-light photoredox-catalyzed formal [5 + 1] cycloaddition of N-tosyl vinylaziridines with difluoroalkyl halides as unique C1 synthons was developed. The procedure provides an efficient and practical method to synthesize diverse pyridines in moderate to good yields. The reaction underwent a radical-initiated kinetically controlled ring-opening of vinylaziridines and involved a key α,β-unsaturated imine intermediate, followed by an E2 elimination, a 6πelectrocyclization, and defluorinated aromatization.

A Bulky Thiyl-Radical Catalyst for the [3+2] Cyclization of N-Tosyl Vinylaziridines and Alkenes

Thiyl-radical-catalyzed cyclization reactions of N-tosyl vinylaziridines and alkenes were developed as a new synthetic method for the generation of substituted pyrrolidines. The key to making this process accessible to a broad range of substrates is the use of a sterically demanding thiyl radical, which prevents the undesired degradation of the catalyst.