82208-33-1Relevant academic research and scientific papers
REGIOSPECIFIC SYNTHESIS OF Δ4-1,2,4-OXADIAZOLIN-3-CARBOXYLIC ACIDS
Pavez, H.,Marquez, A.,Navarrete, S.,Tzichinovsky, S.,Rodriguez, H.
, p. 2223 - 2228 (2007/10/02)
Δ4-1,2,4-Oxadiazolin-3-carboxylic acids, 3a-3i, were obtained by 1,3-dipolar cycloaddition between Δ2-oxazolin-5-ones, 1, and nitrosobenzene, 2.The reaction occurs regiospecifically at room temperature, the mesoionic form of 1 acting
REACTION BETWEEN Δ2-OXAZOLIN-5-ONES AND NITROSOBENZENE. FORMATION OF 1,2,4-OXADIAZOLINES
Rodriguez, H.,Pavez, H.,Marquez, A.,Navarrete, P.
, p. 23 - 27 (2007/10/02)
2,4-diphenyl- and 2-p-methylphenyl-4-phenyl-Δ2-oxazolin-5-ones react at 80-110 deg C with nitrosobenzene to give benzamidines.However, reactions conducted at room temperature afford in high yield, the heretofore undescribed Δ4-oxadiazolin-3-carboxylic acids by regiospecific 1,3-dipolar cycloaddition.Thermal decomposition of the oxadiazolinecarboxylic acids gives the corresponding benzamidines.
