82221-13-4

Basic information

• Product Name: Benzamide, 4-chloro-N-(2-oxo-2-phenylethyl)-
• CAS NO: 82221-13-4
• Molecular Formula: C15H12ClNO2
• Molecular Weight: 273.719
• Mol File: 82221-13-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-chloro-N-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-chloro-N-(2-oxo-2-phenylethyl)-(82221-13-4)
• EPA Substance Registry System: Benzamide, 4-chloro-N-(2-oxo-2-phenylethyl)-(82221-13-4)

Safety Data

• Hazardous Substances Data: 82221-13-4(Hazardous Substances Data)

Upstream product

• 21368-28-5 4-chlorobenzoyl azide 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 74-11-3 para-chlorobenzoic acid 
• 532-27-4 1-chloroacetophenone 
• 5468-37-1 2-aminoacetophenone hydrochloride 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 99923-51-0 ethyl 3-(4-chlorobenzoylamino)-4-oxo-4-phenylbutyrate 
• 99923-67-8 [2-(4-Chloro-phenyl)-5-phenyl-oxazol-4-yl]-acetic acid ethyl ester 
• 24285-73-2 2-(4-chlorophenyl)-5-phenyloxazole 
• 100558-20-1 2-(4-chlorophenyl)-4-phenyl-1H-imidazole 

Relevant articles and documents

RuV-Acylimido Intermediate in [RuIV(Por)Cl2]-Catalyzed C–N Bond Formation: Spectroscopic Characterization, Reactivity, and Catalytic Reactions

Metal-catalyzed C?N bond formation reactions via acylnitrene transfer have recently attracted much attention, but direct detection of the proposed acylnitrenoid/acylimido M(NCOR) (R=aryl or alkyl) species in these reactions poses a formidable challenge. H

Synthesis method of alpha-acylamino ketone compound

The invention discloses a synthesis method of an alpha-acylamino ketone compound, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: mixingan alkenyl azide compound 1, a carboxylic acid compound 2 and an organic solvent, and heating to react to obtain the alpha-acylamino ketone compound 3. Compared with the prior art, the method has thefollowing advantages: (1) the synthesis process is simple and efficient, no catalyst is needed in the whole process, and the alpha-acylamino ketone compound can be obtained with high yield by dissolving the alkenyl azide compound and the carboxylic acid compound in the solvent and stirring; (2) raw materials are cheap and easy to obtain, reaction conditions are mild, and operation is simple; (3) the substrate is wide in application range and can be used for modifying drug molecules; and (4) the atom economy is high, and the requirements of green chemistry are met.

Water-binding solid scintillators: Synthesis, emission properties, and tests in 3H and 14C counting

Spectral and time-resolved fluorescence properties as well as relative fluorescence quantum yields of carbodiimide derivatives of 2,5-diphenyloxazole (PPO) (prepared by H2S elimination from the corresponding thioureas), of some intermediates in the preparation, and of several other PPO derivatives were investigated in solution and in the solid state to test their suitability as solid scintillators. The carbodiimides reacted slowly with water under acidic conditions to yield ureas. These systems were compared with solid mixtures of other PPO derivatives with sodium sulfate as a drying agent, as chemically water-binding solid scintillators in 3H and 14C counting. Both the chemically and the absorptive water-binding scintillators proved capable of counting 3H and 14C decay, and open a way to the counting of aqueous samples by solid scintillators without a drying step.