Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate
CAS No.:82244-11-9
Molecular Formula:C17H21NO4
Molecular Weight:303.358
Hs Code.:
European Community (EC) Number:830-102-8
DSSTox Substance ID:DTXSID40513821
Nikkaji Number:J935.587A

Synonyms:82244-11-9;Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate;BENZYL 4-(2-ETHOXY-2-OXOETHYLIDENE) PIPERIDINE-1-CARBOXYLATE;SCHEMBL2797469;Benzyl4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate;DTXSID40513821;AB8155;MFCD14635597;CS-0238260;EN300-192201

Suppliers and Price of Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:303.14705815
Heavy Atom Count:22
Complexity:403

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=C1CCN(CC1)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

There total 10 articles about Benzyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 1099-45-2
ethyl (triphenylphosphoranylidene)acetate

: 82244-11-9
ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate

Guidance literature:: In toluene; for 18h; Product distribution / selectivity; Heating / reflux;

Reference yield: 85.0%

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 311-46-6
ethyl 2-(dimethoxyphosphoryl)acetate

: 82244-11-9
ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate

Guidance literature:: ethyl 2-(dimethoxyphosphoryl)acetate; With sodium t-butanolate; In tetrahydrofuran; at 0 ℃; for 1h;

benzyl 4-oxo-1-piperidinecarboxylate; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield: 85.0%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 82244-11-9
ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h;

benzyl 4-oxo-1-piperidinecarboxylate; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h;