82292-40-8

Upstream product

• 75-64-9 tert-butylamine 
• 99-63-8 benzene-1,3-dicarbonyl dichloride 
• 626-17-5 benzene-1,3-dicarbonitrile 
• 540-88-5 acetic acid tert-butyl ester 
• 626-19-7 Isophthalaldehyde 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 246230-43-3 2-Sulfanyl-N,N'-di-tert-butylisophthalamide 
• 626-19-7 Isophthalaldehyde 

Relevant academic research and scientific papers

Polyvinylpolypyrrolidone-supported boron trifluoride; Highly efficient catalyst for the synthesis of N-tert-butyl amides

Highly efficient method for the preparation of N-tert-butyl amides by reaction of nitriles with tert-butyl acetate is described using polyvinylpolypyrrolidone-supported boron trifluoride (PVPP-BF3) at 70 °C in good to excellent yields. Selective amidation of benzonitrile in the presence of acetonitrile was also achieved. polyvinylpolypyrrolidone-boron trifluoride complex shows non-corrosive and stable solid catalyst elevated Lewis acid property.

Organic template-free synthesis of zeolite Y nanoparticle assemblies and their application in the catalysis of the Ritter reaction

Zeolite Y nanoparticle assemblies (Y-NA) with a mesoporous structure were directly synthesized at 75?°C for 16 h without adding any organic templates. The changes in structure, morphology and textural parameters of the materials obtained after different crystallization times were investigated via powder X-ray diffraction (XRD), infrared spectroscopy (IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and N2-sorption. The results show that Y-NA had a micro-mesoporous structure composed of highly crystalline particle assemblies with sizes of 400-900 nm. The H-form Y-NA (HY-NA) is strongly acidic, and exhibits a good catalytic performance in the Ritter reaction, as compared with the H-form microporous zeolite Y and mesoporous zeolite ZSM-5.

TfOH catalyzed One-Pot Schmidt–Ritter reaction for the synthesis of amides through N-acylimides

A One-Pot tandem Schmidt–Ritter process for the synthesis of amides has been developed using the super acid as catalyst. The in situ generated aryl/aliphatic nitriles from the reaction of aldehydes and sodium azide in the presence of TfOH and AcOH (Schmidt reaction) react with suitable alcohol (Ritter reaction) to give the amides. For the first time we observed that during the Schmidt process N-acylimides were generated along with nitriles, interestingly these N-acylimides also participated in the Ritter reaction.

Amberlyst-15 as a recyclable heterogeneous catalyst for synthesis of N-tert-butylamides via Ritter-type reaction

Highly efficient method for the preparation of N-tert-butylamides by reaction of nitriles with tert-butylacetate is described using Amberlyst-15 as a recyclable heterogeneous catalyst. Selective amidation of benzonitrile in the presence of acetonitrile was also achieved.

Synthesis of benzisochalcogenol and -azole derivatives via ortho metalation of isophthalamides

The syntheses of benzofused isochalcogenazole derivatives via ortho-lithiation of isophthalamides is reported. N,N′-Dialkyl-isophthalamides, C6H4-1,3-(CONHR)2, bearing R = iPr or tBu substituents are readily ortho metalate