82296-08-0

Usage

Chemical compound

4H-Imidazo[2,1-c][1,4]benzoxazine

Class

Heterocyclic compounds

Structure

Contains atoms other than carbon in its ring structure

Moiety

Benzoxazine

Uses

Synthesis of pharmaceuticals and agrochemicals

Biological activities

Anti-tumor, anti-inflammatory, anti-convulsant

Applications

Development of new drugs, ongoing research in medicinal chemistry and chemical biology

Potential in materials science

Building block for novel polymers and advanced materials

Upstream product

• 121608-17-1 N-(2H-1,4-benzoxazin-3-yl)aminoacetaldehyde dimethyl acetal 
• 21744-76-3 3-methylthio-2H-1,4-benzoxazine 
• 65565-71-1 methyl 2-(chloroacetamido)-2-<2-oxo-2H-1,4-benzoxazin-3-yl>acetate 
• 95-55-6 2-amino-phenol 
• 65565-69-7 methyl 2-hydroxyimino-2-<2-oxo-2H-1,4-benzoxazin-3-yl>acetate 
• 65565-70-0 methyl 2-amino-2-<2-oxo-2H-1,4-benzoxazin-3-ylidene>acetate 
• 66628-73-7 (2Z)-[2-oxo-2H-1,4-benzoxazine-3(4H)-ylidene]acetic acid methyl ester 
• 65565-85-7 2-methoxycarbonyl-4H-imidazo<2,1-c><1,4>benzoxazine-1-carboxylic acid 
• 65565-73-3 4H-imidazo<2,1-c><1,4>benzoxazine-2-carboxylic acid 
• 65565-72-2 methyl 4H-imidazo<2,1-c><1,4>benzoxazine-2-carboxylate 

Relevant academic research and scientific papers

Studies on the Chemistry of 1,4-Oxazines. 18. Synthesis of Tricyclic 1,4-Benzoxazines via Nucleophilic Substitution of Activated Precursors

Starting from activated benzoxazines 1 and 2 new synthetic pathways to the tricyclic compounds 4, 9, 12 and 16 are described.Reaction of the hydrazides 17a,b with thionylchloride leads to the novel thiatriazolobenzoxazines 18a,b.

Synthesis and Reactions of Some Novel Imidazobenzoxazines and Related Systems

A novel synthesis of the new 4H-imidazobenzoxazine system (2) has been carried out under two sets of conditions, leading to products with differing functionalities.The effect of substituents on the cyclization step has been investigated and the reactions of the functional groups of the new ring system have been studied.Derivatives of the related 4,5-dihydroimidazobenzoxazepine (3) have also been prepared.