82297-65-2Relevant academic research and scientific papers
One-pot synthesis of (E)-styryl ketones from styrenes
Pawluc, Piotr,Szudkowska, Justyna,Hreczycho, Grzegorz,Marciniec, Bogdan
, p. 6438 - 6441 (2011/09/15)
A new, efficient protocol for the highly stereoselective one-pot synthesis of (E)-styryl ketones from styrenes based on sequential ruthenium-catalyzed silylative coupling-rhodium-catalyzed desilylative acylation reactions is reported.
Regioselective heck vinylation of electron-rich olefins with vinyl halides: Is the neutral pathway in operation?
McConville, Matthew,Saidi, Ourida,Blacker, John,Xiao, Jianliang
experimental part, p. 2692 - 2698 (2009/08/15)
Highly regioselective vinylation of electron-rich olefins by bromo- as well as chlorostyrenes is effected by palladium catalysis with either mono- or bidentate phosphines in a molecular solvent, with no need for halide scavengers, ionic liquids, or ionic additives. The use of the hemilabile 1,3-bis(diphenylphosphino)propane monoxide (dpppO) as a ligand led to faster reactions of more challenging 2-substituted vinyl ethers and reduced Pd loadings. In contrast to the related arylation reaction, evidence suggests that the vinylation may proceed via the neutral Heck mechanism.
