823-17-6Relevant academic research and scientific papers
Effect of ketene additive and Si/Al ratio on the reaction of methanol over HZSM-5 catalysts
Hassanpour, Javad,Zamani, Mehdi,Dabbagh, Hossein A.
, (2018/03/01)
The influence of ketene as possible intermediate for the reaction of methanol to aromatics was investigated over HZSM-5 catalysts (Si/Al ratio of 15 and 9) using diketene-acetone (2,2,6-trimethyl-4H-1,3-dioxin-4-one) as ketene precursor under atmospheric
Fused cycloalkyl amides and acids and their therapeutic applications
-
, (2008/06/13)
The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
Fused cycloalkyl amides and acids and their therapeutic applications
-
, (2008/06/13)
The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
Electrophilic substitution with allylic rearrangement (SE′) stereochemistry of trifluoroacetolysis of some cyclohex-2-enylmetal compounds
Wickham, Geoffrey,Young, David,Kitching, William
, p. 1187 - 1195 (2008/10/08)
A range of (4-alkylcyclohex-2-enyl)-, (5-alkylcyclohex-2-enyl)-, and (6-alkylcyclohex-2-enyl)silanes, (4-alkylcyclohex-2-enyl)-, (5-alkylcyclohex-2-enyl)-, and (6-alkylcyclohex-2-enyl)germanes, and (4-alkyl-cyclohex-2-enyl)-, (5-alkylcyclohex-2-enyl)-, and (6-alkylcyclohex-2-enyl)stannanes were cleaved to the cycloalkene (and R3MX) with trifluoroacetic acid-d in various solvents. Complete allylic rearrangement (γ-attack) was observed, and the preferred direction of delivery of the electrophile (formally D+) to the γ-carbon of the allylic triad was determined by detailed 1H, 13C, and 2H NMR analyses of the derived dibromides of the various alkyl-substituted cyclohexenes or by direct 2H NMR analysis and comparisons with 2H-substituted alkylcyclohexenes of established relative configurations. A highly preferred γ-anti mode of acidolysis is established for all systems, except for the trans-4-tert-butylcyclohex-2-enyl derivatives, such exception being ascribed to steric impedance of electrophile approach, promoting syn attack. Thus, overall, highly γ-regioselective and anti-stereoselective substitutions (SE′) are observed.
Electrophilic Substitution with Allylic Rearrangement (SE'). Anti Stereoselectivity in Trifluoroacetolysis of Some Cyclohex-2-enylsilanes, -germanes, and -stannanes
Wickham, Geoffrey,Kitching, William
, p. 612 - 614 (2007/10/02)
Trifluoroacetolysis of various cyclohex-2-enylsilanes, -germanes, and -stannanes is demonstrated to be γ regiospecific and highly anti stereoselective, as predicted for a dominating LUMO-HOMO interaction in a concerted SE2'process.
