823-70-1Relevant academic research and scientific papers
Mechanistic Studies on Zinc-Induced Addition of CF2Br2 to Olefins. A Novel Radical Reductive Cyclopropanation on the Zinc Surface
Wu, Shi-Hui,Liu, Wei-Zhong,Jiang, Xi-Kui
, p. 854 - 857 (2007/10/02)
The addition reaction of dibromodifluoromethane (1) to olefins induced by zinc in ethereal solvent differs surprisingly from addition reactions hitherto reported.Both cyclopropane derivatives and 1:1 addition products were obtained from this reaction.A free-radical chain addition reaction induced by single electron transfer (SET) is proposed.This reaction is inhibited by hydroquinone and completely quenched by p-dinitrobenzene.The nature of the 1:1 adducts formed revealed the character of a typical radical reaction.The nature of the cyclopropane derivatives formed was also much different from the usual cyclopropane adduct derived from carbene addition.When diallyl ether (15) and norbornadiene (16) were used as substrates, only rearranged 1:1 addition products could be obtained, and no cyclopropane product could be detected.The results of addition reactions with 4-octenes (27) showed also that the cyclopropanation reaction was not stereospecific.On the basis of the above-mentioned results, a novel reductive debromocyclopropanation reaction of the γ-bromopropyl radical intermediate proceeding on the zinc metal surface is suggested.
(CF3)2Cd*D UND (CF3)2Zn*D: NEUE REAGENZIEN FUER DIFLUORCARBEN-REAKTIONEN
Lange, Horst,Naumann, Dieter
, p. 299 - 308 (2007/10/02)
During the thermal decomposition of (CF3)2Cd and (CF3)2Zn complexes primarily difluorocarbene is eliminated.The formation of CF2 is unambiguously proved by matrix i.r. spectroscopy.Both (CF3)2Cd*D and (CF3)2Zn*D are excellent CF2 sources, which can easily be prepared and handled, and which undergo CF2 reactions even at low temperature.CF2 insertion was found during the reaction of (CF3)2Te with (CH3)2Cd via the intermediate formation of a CF3Cd compound to form CH3TeCF2CH3. (CF3)2Cd*glyme reacts with (CH3)3Si(OCOCF3) to CF3Cd(OCOCF3)*glyme; during this reaction CF2 is also eliminated.
Cyclopropane Chemistry. Part 4. The Reactions of 1,2,2-Trifluoroethylidene with Alkenes and Pyrolysis of the Resulting Cyclopropanes
Haszeldine, Robert N.,Rowland, Ronald,Speight, James G.,Tipping, Anthony E.
, p. 314 - 324 (2007/10/02)
1,2,2-Trifluoroethylidene, generated by the pyrolysis of (1,1,2,2-tetrafluoroethyl)trifluorosilane, reacts with tetrafluoroethylene, ethylene, and a series of methyl-substituted ethylenes to give the corresponding 1-fluoro-1-difluoromethylcyclopropanes in good yield; cyclohexene gives the corresponding norcarane, and tris(trifluoromethyl)phosphine gives the corresponding phosphorane (CF3)3P(+)-C(-)F-CHF2.Pyrolysis of 1,2,2,3,3-pentafluoro-1-difluoromethylcyclopropane affords difluorocarbene and 3H-pentafluoropropene, but pyrolysis of the methyl-substituted cyclopropanes results in the formation of dienes in high yield, e.g. the 1,4-dienes CHF=CF-CMeR-CMe=CH2 from the cyclopropanes (R = H or Me) or 1,3-dienes from the methyl-substituted cyclopropanes, e.g. --> CH2=CMe-C(CHF2)=CH2.In certain cases further dehydrofluorination of the 1,3-dienes affords trienes, e.g. --> CH2=CMe-C(=CHF)-CMe=CH2.
