82301-69-7Relevant academic research and scientific papers
One-pot process to Z-α-benzoylamino-acrylic acid methyl esters via potassium phosphate-catalyzed Erlenmeyer reaction
Cleary, Thomas,Brice, Jodie,Kennedy, Nicole,Chavez, Flavio
supporting information; experimental part, p. 625 - 628 (2010/04/05)
A practical and efficient two reaction sequence one-pot process for the synthesis of Z-α-benzoylamino-acrylic acid methyl esters was developed. The process involves a potassium phosphate-catalyzed Erlenmeyer reaction of aromatic aldehydes with hippuric acid followed by an oxazolone ring-opening methanolysis. This process afforded a good overall yield and an excellent product quality via a simple workup.
Practical preparation of Z-α-(N-acetylamino)- and Z-α-(N-benzoylamino)-α,β-unsaturated acids
Jursic, Branko S.,Sagiraju, Sarada,Ancalade, Dustin K.,Clark, Traneil,Stevens, Edwin D.
, p. 1709 - 1714 (2008/02/01)
An efficient two-step synthetic procedure for the preparation of numerous variations of N-protected α,β-unsaturated α-amino acids and their corresponding esters from N-protected glycine and either aliphatic or aromatic aldehydes was developed. The reaction involved cyclization of the N-protected glycine into oxazolone, condensation with the aldehyde, and ring opening with a base. Copyright Taylor & Francis Group, LLC.
An usual behaviour of ethers in presence of azlactones under ultrasound irradiation to give esters
Rajaram, S.,Lalitha, N.,Iyengar, D. S.
, p. 761 - 763 (2007/10/03)
The phenomenon of ester formation from ethers and azlactones under sonolysis has been observed.
