82343-11-1

Basic information

• Product Name: (-)-4'-O-p-Nitrobenzoyl-N-trifluoroacetyl-4-demethoxydaunorubicin
• CAS NO: 82343-11-1
• Molecular Weight: 742.616
• Mol File: 82343-11-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (-)-4'-O-p-Nitrobenzoyl-N-trifluoroacetyl-4-demethoxydaunorubicin(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-4'-O-p-Nitrobenzoyl-N-trifluoroacetyl-4-demethoxydaunorubicin(82343-11-1)
• EPA Substance Registry System: (-)-4'-O-p-Nitrobenzoyl-N-trifluoroacetyl-4-demethoxydaunorubicin(82343-11-1)

Safety Data

• Hazardous Substances Data: 82343-11-1(Hazardous Substances Data)

Upstream product

• 63700-24-3 2,3,6-trideoxy-4-O-(p-nitrobenzoyl)-3-(trifluoroacetamido)-α-L-lyxo-hexopyranosyl p-nitrobenzoate 
• 60660-75-5 (7S,9S)-idarubicinone 
• 63700-25-4 1-chloro-2,3,6-trideoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-L-lyxohexopyranose 
• 52583-22-9 2,3,6-trideoxy-1,4-di-O-p-nitrobenzoyl-3-trifluoroacetamido-L-lyxopyranose 
• 128572-89-4 4-Nitro-benzoic acid (2S,3R,4S)-6-chloro-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester 

Downstream Products

• 62414-03-3 (7S,9S)-9-acetyl-7-<(3'-amino-2',3',6'-trideoxy-α-L-arabinohexopyranosyl)oxy>-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione 
• 57852-57-0 idarubicin hydrochloride 
• 58957-92-9 idarubicin 
• 60660-74-4 (+)-N-Trifluoroacetyl-4-demethoxydaunorubicin 

Relevant articles and documents

Synthesis and antitumor activity of novel 4-demethoxyanthracyclines

A versatile and efficient synthetic route to 4-demethoxyanthracyclinones has been utilized in the preparation of a number of aglycons having 9-alkyl, 9-(hydroxylalkyl), or 9-carbamoyl substituents. Silver trifluoromethanesulfonate catalyzed coupling of th

Total Synthesis of 4-Demethoxydaunomycin

The Diels-Alder adduct prepared from the optically active, fully functionalised bicyclic precursor (8) and o-benzoquinone dimethide has been converted in good yield inmto (+)-4-demethoxydaunomycinone (13), glycosidation of which with the daunosamine derivative (14) gives 4-demethoxydaunomycin.