60660-74-4 Usage
General Description
(+)-N-Trifluoroacetyl-4-demethoxydaunorubicin, also known as TF3, is a synthetic derivative of the chemotherapy drug daunorubicin. It is commonly used in the treatment of various types of cancer, including leukemia, lymphoma, and solid tumors. The addition of a trifluoroacetyl group to the daunorubicin molecule enhances its stability and bioavailability, making it more effective in targeting cancer cells. TF3 works by inhibiting the growth of cancer cells and inducing cell death, and may also have anti-angiogenic properties. Its unique chemical structure and pharmaceutical properties make it a promising candidate for the development of new and improved cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 60660-74-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,6 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 60660-74:
(7*6)+(6*0)+(5*6)+(4*6)+(3*0)+(2*7)+(1*4)=114
114 % 10 = 4
So 60660-74-4 is a valid CAS Registry Number.
60660-74-4Relevant articles and documents
Total Synthesis of 4-Demethoxydaunomycin
Broadhurst, Michael J.,Hassall, Cedric H.,Thomas, Gareth J.
, p. 158 - 160 (1982)
The Diels-Alder adduct prepared from the optically active, fully functionalised bicyclic precursor (8) and o-benzoquinone dimethide has been converted in good yield inmto (+)-4-demethoxydaunomycinone (13), glycosidation of which with the daunosamine derivative (14) gives 4-demethoxydaunomycin.
