82358-61-0 Usage
Uses
Used in Organic Synthesis:
Cyanomethyltri-n-butylphosphonium chloride is used as a phase transfer catalyst for enhancing the efficiency of various organic reactions. Its ability to transfer reactants between phases makes it a valuable tool in the synthesis of complex organic molecules.
Used in Pharmaceutical and Agrochemical Industries:
In the pharmaceutical and agrochemical sectors, cyanomethyltri-n-butylphosphonium chloride is utilized as a phase-transfer catalyst in the synthesis of active ingredients. Its role in facilitating reactions that are crucial for the production of these compounds underscores its importance in these industries.
Used in the Synthesis of Chemical Intermediates:
Cyanomethyltri-n-butylphosphonium chloride is also employed in the synthesis of a range of chemical intermediates. These intermediates are essential building blocks in the production of various chemicals and materials, highlighting the compound's broad applicability in the chemical industry.
Used as a Mild Nucleophile in Organic Reactions:
Furthermore, cyanomethyltri-n-butylphosphonium chloride serves as a mild nucleophile in organic reactions. Its nucleophilic properties allow it to participate in a variety of substitution and addition reactions, contributing to the formation of desired products with minimal side reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 82358-61-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,5 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 82358-61:
(7*8)+(6*2)+(5*3)+(4*5)+(3*8)+(2*6)+(1*1)=140
140 % 10 = 0
So 82358-61-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H29NP/c1-4-7-11-16(14-10-15,12-8-5-2)13-9-6-3/h4-9,11-14H2,1-3H3/q+1
82358-61-0Relevant academic research and scientific papers
A Convenient Method for the Asymmetric Synthesis of Fluorinated α-Amino Acids from Alcohols
Drouet, Fleur,Noisier, Anas F. M.,Harris, Craig S.,Furkert, Daniel P.,Brimble, Margaret A.
supporting information, p. 1195 - 1201 (2015/10/05)
Due to their numerous applications, fluorinated amino acids have recently attracted significant attention. The preparation of fluorine-containing phenylalanines, heteroaryl alanines and aliphatic fluorinated amino acids using Mitsunobu-Tsunoda alkylation of a chiral nucleophilic glycine equivalent with readily available alcohol substrates is described. The reaction proceeds in high yields and with excellent diastereoselectivity. This method provides an efficient synthetic route to fluorinated amino acids for which asymmetric approaches are scarce.
Preparation of (cyanomethylene)tributylphosphorane: A new mitsunobu-type reagent
Sakamoto, Izumi,Nishii, Takeshi,Ozaki, Fumie,Kaku, Hiroto,Tanaka, Masami,Tsunoda, Tetsuto
, p. 1508 - 1509 (2007/10/03)
(Cyanomethylene)tributylphosphorane (CMBP), which promoted the alkylation of various nucleophiles (HA) with alcohols (ROH) to give RA (Mitsunobu-type reaction), was prepared in two steps starting from chloroacetonitrile.
Novel reactivity of stabilized methylenetributylphosphorane: A new mitsunobu reagent
Tsunoda, Tetsuto,Ozaki, Fumie,Ito, Sho
, p. 5081 - 5082 (2007/10/02)
Cyanomethylenetributylphosphorane was shown to mediate the direct condensation of alcohols with O- and N-nucleophiles. A secondary alcohol, 2- octanol, reacted satisfactorily with Walden inversion of its carbinyl carbon.
