82380-17-4

Upstream product

• 36282-26-5 2-bromo-4-fluorobenzonitrile 
• 140860-51-1 2-bromo-4-methoxy benzonitrile 

Downstream Products

• 140860-51-1 2-bromo-4-methoxy benzonitrile 
• 136240-38-5 4'-Pentyl-biphenyl-4-carboxylic acid 3-bromo-4-cyano-phenyl ester 
• 136240-36-3 4-(4-Pentyl-cyclohexyl)-benzoic acid 3-bromo-4-cyano-phenyl ester 
• 22532-60-1 2-bromo-4-hydroxybenzaldehyde 
• 1415599-55-1 1,1-dimethyl-6-(4-nitrophenoxy)-1,3-dihydro-2-benzofuran 
• 1415599-57-3 4-[(3,3-dimethyl-1,3-dihydro-2-benzofuran-5-yl)oxy]aniline 
• 1415599-58-4 (2R)-2-amino-N-[4-[(3,3-dimethyl-1H-isobenzofuran-5-yl)oxy]phenyl]-2-methyl-butanamide 
• 1415598-70-7 (5R)-3-{4-[(3,3-dimethyl-1,3-dihydro-2-benzofuran-5-yl)oxy]phenyl}-5-ethyl-5-methyl-2,4-imidazolidinedione 
• 1415598-75-2 [2-bromo-4-[tert-butyl(dimethyl)silyl]oxyphenyl]methanol 
• 609347-96-8 2-bromo-4-(tert-butyl-dimethyl-silanyloxy)-benzaldehyde 
• 1415598-76-3 2-[5-[tert-butyl(dimethyl)silyl]oxy-2-(hydroxymethyl)phenyl]propan-2-ol 

Relevant academic research and scientific papers

SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING

A compound of formula (I), wherein: R1 is selected from (i) H, (ii) C3-6cycloalkyl, (iii) C3-7heterocyclyl optionally substituted with a group selected from: methyl and ester, and (iv) linear or branched C1-4alkyl optionally substituted with a group selected from: alkoxy, amino, amido, acylamido, acyloxy, alkyl carboxyl ester, alkyl carbamoyl, alkyl carbamoyl ester, phenyl, phosphonate ester, C3-7heterocyclyl optionally substituted with a group selected from methyl and oxo, and a naturally occurring amino acid, optionally N-substituted with a group selected from methyl, acetyl and boc; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC, and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and CH2NMe2; the remainder of RA, RB, RC, and RD, (if present) are H; Y is O, NH or CH2; RY is selected from: (RYA) and (RYB).

SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS USEFUL AS GPR120 AGONISTS

The present invention relates to a compound represented by formula (I) and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related di

HYDANTOIN DERIVATES AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES

The present invention relates to polysubstituted imidazolone derivatives, to the pharmaceutical compositions comprising them and to the therapeutic uses thereof in the human and animal health fields. The present invention also relates to a process for preparing these derivatives.