1415599-57-3

Upstream product

• 36282-26-5 2-bromo-4-fluorobenzonitrile 
• 22532-60-1 2-bromo-4-hydroxybenzaldehyde 
• 82380-17-4 2-bromo-4-hydroxybenzonitrile 
• 1415599-55-1 1,1-dimethyl-6-(4-nitrophenoxy)-1,3-dihydro-2-benzofuran 
• 1415598-75-2 [2-bromo-4-[tert-butyl(dimethyl)silyl]oxyphenyl]methanol 
• 609347-96-8 2-bromo-4-(tert-butyl-dimethyl-silanyloxy)-benzaldehyde 
• 1415598-76-3 2-[5-[tert-butyl(dimethyl)silyl]oxy-2-(hydroxymethyl)phenyl]propan-2-ol 
• 1415598-84-3 3,3-dimethyl-1H-isobenzofuran-5-ol 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 1415599-58-4 (2R)-2-amino-N-[4-[(3,3-dimethyl-1H-isobenzofuran-5-yl)oxy]phenyl]-2-methyl-butanamide 
• 1415598-70-7 (5R)-3-{4-[(3,3-dimethyl-1,3-dihydro-2-benzofuran-5-yl)oxy]phenyl}-5-ethyl-5-methyl-2,4-imidazolidinedione 

Relevant academic research and scientific papers

HYDANTOIN DERIVATIVES AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

ISOBENZOFURAN- 5 -YL-OXY- (HETERO) ARYL - IMIDAZOLIDINE - 2, 4 -DIONE DERIVATIVES MODULATORS OF KV3 POTASSIUM CHANNELS FOR THE TREATMENT OF CNS DISORDERS.

The invention provides compounds of the general type: (Formula (I)). Said compounds being modulators of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

HYDANTOIN DERIVATES AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.