82380-67-4Relevant academic research and scientific papers
An efficient synthesis and biological study of novel indolyl-1,3,4-oxadiazoles as potent anticancer agents
Kumar, Dalip,Sundaree, Swapna,Johnson, Emmanuel O.,Shah, Kavita
scheme or table, p. 4492 - 4494 (2010/04/05)
A facile, convenient and high yielding synthesis of a series of novel 5-(3′-indolyl)-2-(substituted)-1,3,4-oxadiazoles from readily available starting materials has been described. The key step of this protocol is oxidative cyclization of N-acylhydrazones
Synthesis and properties of azoles and their derivatives. 33. Synthesis of 1,3,4-oxadiazoles that contain an indolyl group
Kelarev,Shvekhgeimer
, p. 258 - 261 (2007/10/02)
2,5-Disubstituted oxadiazoles with indole residues were synthesized by condensation of the hydrochlorides of the corresponding imido esters with hydrazines, as well as by cyclization of hydrazides by the action of POCl3. 2-Substituted oxadiazoles of the same series were obtained by condensation of the corresponding hydrazides with ethyl orthoformate.
