82458-45-5

Upstream product

• 100-44-7 benzyl chloride 
• 82448-61-1 2',4',5,7-tetrakis(benzyloxy)flavanone 
• 82448-60-0 2,4,4',6'-tetrakis(benzyloxy)-2'-hydroxychalcone 
• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 369371-85-7 Acetic acid 3,5-bis-benzyloxy-2-[(E)-3-(2,4-bis-benzyloxy-phenyl)-acryloyl]-phenyl ester 
• 120980-05-4 (E)-1-(2,4-Bis-benzyloxy-6-hydroxy-phenyl)-3-(2,4-bis-benzyloxy-phenyl)-propenone 
• 67052-53-3 4',6'-bis(benzyloxy)-2'-(methoxymethoxy)acetophenone 
• 369371-86-8 acetic acid 3,5-bis-benzyloxy-2-[2-(2,4-bis-benzyloxy-phenyl)-3,3-dimethoxy-propionyl]-phenyl ester 
• 82448-62-2 2'-acetoxy-2,4,4',6'-tetrakis(benzyloxy)chalcone 

Downstream Products

• 1156-78-1 2',4',5,7-tetrahydroxyisoflavone 
• 82448-63-3 2',4',7-tris(benzyloxy)-5-hydroxyisoflavone 
• 66056-19-7 licoisoflavone A 
• 66056-27-7 2',4',5,7-tetraacetoxy-3'-(3-methyl-2-butenyl)isoflavone 
• 82448-67-7 2',4',5,7-tetrahydroxy-5'-(3-methyl-2-butenyl)isoflavone 
• 82448-65-5 5-benzoyloxy-2',4',7-trihydroxyisoflavone 
• 82448-69-9 7-benzoyloxy-2',4',5-trihydroxyisoflavone 
• 82448-64-4 5-benzoyloxy-2',4',7-tris(benzyloxy)isoflavone 
• 96909-22-7 2',4',5,7-tetrahydroxy-3',5'-bis(3-methyl-2-butenyl)isoflavone 
• 96909-21-6 5-benzoyloxy-2',4',7-trihydroxy-3',5'-bis(3-methyl-2-butenyl)isoflavone 
• 96909-31-8 7-benzoyloxy-2',4',5-trihydroxy-3',5'-bis(3-methyl-2-butenyl)isoflavone 
• 96909-24-9 2',4',5,7-tetraacetoxy-5'-(3-methyl-2-butenyl)isoflavone 
• 96909-23-8 2',4',5,7-tetraacetoxy-3',5'-bis(3-methyl-2-butenyl)isoflavone 
• 98094-87-2 Lupinalbin A 

Relevant academic research and scientific papers

Facile synthesis of polyhydroxycoumaronochromones with quinones: Synthesis of alkylpolyhydroxy- and alkoxycoumaronochromones from 2′-hydroxyisoflavones

4′,5,7-Trihydroxy- or 8-alkyl-4′,5,7-trihydroxycoumaronochromones were synthesized by oxidative cyclization of the corresponding 2′-hydroxyisoflavones with o-chloranil under mild conditions. By contrast, alkoxycoumaronochromones were synthesized by oxidative cyclization of the corresponding 2′-hydroxyisoflavones with DDQ.

Synthesis of Licoisoflavone A and Related Compounds

2',4',5,7-Tetrahydroxyisoflavone was partially benzoylated with benzoyl chloride to give 7-benzoyloxy-2',4',5-trihydroxyisoflavone.The condensation of the 7-(benzoyloxy)isoflavone with 2-methyl-3-buten-2-ol, followed by the hydrolysis of the resultant 3'-(3-methyl-2-butenyl)isoflavone gave licoisoflavone A.Its 5'-(3-methyl-2-butenyl) isomer was also synthesized from 5-benzoyloxy-2',4',7-trihydroxyisoflavone in a similar manner.

SYNTHESES OF LICOISOFLAVONE A AND 5'-ALKENYL ISOMER

2',4',5,7-Tetrahydroxyisoflavone was partially benzoylated with benzoyl chloride to give 7-benzoyloxy-2',4',5-trihydroxyisoflavone.The condensation of 7-benzoyloxyisoflavone with 2-methyl-3-buten-2-ol, followed by the hydrolysis of the resultant 3'-(3-met