82475-74-9 Usage
Uses
Used in Pharmaceutical Industry:
Trimethylsilyl bis(2-chloroethyl)carbamate is used as an intermediate in the synthesis of chemotherapeutic drugs and other pharmaceuticals for its alkylating agent properties, which can disrupt the replication of cancerous cells.
Used in Pesticide Production:
Trimethylsilyl bis(2-chloroethyl)carbamate is used as a chemical intermediate in the production of pesticides, contributing to the development of effective agents for pest control.
Used in Herbicide Production:
Similarly, in the herbicide industry, trimethylsilyl bis(2-chloroethyl)carbamate is utilized as an intermediate, playing a role in the creation of herbicidal compounds designed to control or kill unwanted plants.
Used in Antineoplastic Agent Synthesis:
Trimethylsilyl bis(2-chloroethyl)carbamate is employed as a key intermediate in the synthesis of antineoplastic agents, which are drugs that inhibit the growth and spread of tumors.
It is crucial to handle trimethylsilyl bis(2-chloroethyl)carbamate with care due to its toxic nature and potential hazards to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 82475-74-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,4,7 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 82475-74:
(7*8)+(6*2)+(5*4)+(4*7)+(3*5)+(2*7)+(1*4)=149
149 % 10 = 9
So 82475-74-9 is a valid CAS Registry Number.
82475-74-9Relevant academic research and scientific papers
Synthesis, hydrolytic reactivity, and anticancer evaluation of N-and O-triorganosilylated compounds as new types of potential prodrugs
Chiu,Chang,Ozkan,Zon,Fichter,Phillips
, p. 542 - 551 (2007/10/02)
N- and O-Triorganosilylated compounds related to various anticancer agents were synthesized for evaluation as potential anticancer prodrugs. 1H-NMR and UV kinetic measurements of hydrolytic desilylation were used to correlate relative rates of structural unmasking with steric bulk about the silicon reaction center. The tert-butyldimethylsilyl ester of chlorambucil and a number of O-triorganosilylated carbamate derivatives of nor-nitrogen mustard showed significant activity against P-388 lymphocytic leukemia in mice.
