825-19-4Relevant academic research and scientific papers
Deoxygenation of tertiary amine N-oxides under metal free condition using phenylboronic acid
Gupta, Surabhi,Sureshbabu, Popuri,Singh, Adesh Kumar,Sabiah, Shahulhameed,Kandasamy, Jeyakumar
supporting information, p. 909 - 913 (2017/02/15)
A simple and efficient method for the deoxygenation of amine N-oxides to corresponding amines is reported using the green and economical reagent phenylboronic acid. Deoxygenation of N,N-dialkylaniline N-oxides, trialkylamine N-oxides and pyridine N-oxides were achieved in good to excellent yields. The reduction susceptible functional groups such as ketone, amide, ester and nitro groups are well tolerated with phenylboronic acid during the deoxygenation process even at high temperature. In addition, an indirect method for identification and quantification of tert-amine N-oxide is demonstrated using UV–Vis spectrometry which may be useful for drug metabolism studies.
Rhenium-catalyzed highly efficient oxidations of tertiary nitrogen compounds to N-oxides using sodium percarbonate as oxygen source
Jain, Suman L.,Joseph, Jomy K.,Sain, Bir
, p. 2661 - 2663 (2008/09/16)
Sodium percarbonate was found to be an ideal and efficient oxygen source for the oxidation of tertiary nitrogen compounds to N-oxides in excellent yields in presence of various rhenium-based catalysts under mild reaction conditions. Georg Thieme Verlag Stuttgart.
OPTICAL RESOLUTION OF AMINE N-OXIDE BY DIASTEREOISOMERIC COMPLEX FORMATION WITH OPTICALLY ACTIVE HOST COMPOUND
Toda, Fumio,Mori, Koji
, p. 1841 - 1844 (2007/10/02)
Optical stereoisomers of various amine N-oxides with one or two chiral centers can effectively be resolved by selective crystalline complexation with an optically active host.Intermolecular interaction schemes and absolute configurations of the N-oxide guests are revealed by crystallographic analyses of the diastereoisomeric complexes.
