825-80-9

Upstream product

• 121-72-2 N,N-dimethyl-m-toluidine 

Downstream Products

• 10192-53-7 2-(N,N-dimethylamino)-6-methylphenol 
• 30427-16-8 2-(N,N-dimethylamino)-4-methylphenol 
• 1616786-34-5 2-(N,N-dimethylamino)-4-methylphenyl trifluoromethanesulfonate 
• 1616786-35-6 2-(N,N-dimethylamino)-6-methylphenyl trifluoromethanesulfonate 
• 1616786-49-2 ethyl (2-(N,N-dimethylamino)-4-methylphenyl)acetate 
• 1616786-50-5 ethyl (2-(N,N-dimethylamino)-6-methylphenyl)acetate 
• 50638-50-1 3-methyl-4-bromo-N,N-dimethylaniline 
• 75560-71-3 4-chloro-3-methyl-N,N-dimethylaniline 
• 1610871-11-8 1,6-dimethyl-2,3-diphenyl-1H-indole 

Relevant academic research and scientific papers

THE MECHANISTIC MODE OF OXIDATION OF SUBSTITUTED N,N-DIMETHYLANILINES, THIOANISOLES, AND METHYL PHENYL SULFOXIDES BY 5-ETHYL-4a-HYDROPEROXY-3-METHYL-LUMIFLAVIN (4a-FlEt-OOH)

In the oxidation of the title compounds, 5-ethyl-4a-hydroperoxy-3-methyl-lumiflavin (4a-FlEt-OOH), was found to be an electrophilic oxidant similar to m-chloroperoxybenzoic acid.However, the stereoselectivity of the oxidation of cyclic sulfides to the corresponding sulfoxides by 4a-FlEt-OOH was less pronounced than that of the oxygenation with flavin-containing monooxygenase.

Catalytic N-oxidation of tertiary amines on RuO2NPs anchored graphene nanoplatelets

Ultrafine ruthenium oxide nanoparticles (RuO2NPs) with an average diameter of 1.3 nm were anchored on graphene nanoplatelets (GNPs) using a Ru(acac)3 precursor by a very simple dry synthesis method. The resultant material (GNPs-RuO2NPs) was used as a heterogeneous catalyst for the N-oxidation of tertiary amines for the first time. The transmission electron microscopy (TEM) images of the GNPs-RuO2NPs showed the excellent attachment of RuO2NPs on GNPs. The loading of Ru in GNPs-RuO2NPs was 2.68 wt%, as confirmed by scanning electron microscope-energy dispersive spectroscopy (SEM-EDS). The X-ray photoelectron spectrum (XPS) and the X-ray diffraction pattern (XRD) of GNPs-RuO 2NPs revealed that the chemical state of Ru on GNPs was +4. After the optimization of reaction conditions for N-oxidation of triethylamine, the scope of the reaction was extended to various aliphatic, alicyclic and aromatic tertiary amines. The GNPs-RuO2NPs showed excellent catalytic activity in terms of yields even at a very low amount of Ru catalyst (0.13 mol%). The GNPs-RuO2NPs was heterogeneous in nature, chemically as well as physically, very stable and could be reused up to 5 times. The Royal Society of Chemistry 2014.

Metal-free functionalization of N, N-dialkylanilines via temporary oxidation to N, N-dialkylaniline N-oxides and group transfer

A simple set of protocols for the controlled elaboration of anilines is reported allowing access to a diverse array of aminophenols, aminoarylsulfonates, alkylated anilines, and aminoanilines in 29-95% yield in a single laboratory operation from easily isolable, bench-stable N,N-dialkylaniline N-oxides. The introduction of new C-O, C-C, and C-N bonds on the aromatic ring is made possible by a temporary increase in oxidation level and excision of a weak N-O bond.