82545-65-1Relevant academic research and scientific papers
Cobalt-Mediated 1,4-Acylation/Alkylation of 1,3-Dienes
Hegedus, Louis S.,Inoue, Yoshio
, p. 4917 - 4921 (1982)
Acylcobalt complexes prepared from NaCo(CO)4 and organic halides reacted with butadiene, isoprene and allene to form (acyl-?-allyl)cobalt complexes.Reaction of these with stabilized carbanions resulted in alkylation at the unsubstituted ?-allyl terminus.The procedure provides an overall 1,4-acylation/alkylation of 1,3-dienes in which three carbon-carbon bonds are formed in a one-pot, four-step reaction sequence.
