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(2S)-2-(3,5-bis(trifluoromethyl)phenyl)-N-[4-(4-fluoro-2-methylphenyl)-6-(2-hydroxymethylpyrrolidin-1-yl)pyridin-3-yl]-N-methylisobutyramide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

825640-97-9

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825640-97-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 825640-97-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,5,6,4 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 825640-97:
(8*8)+(7*2)+(6*5)+(5*6)+(4*4)+(3*0)+(2*9)+(1*7)=179
179 % 10 = 9
So 825640-97-9 is a valid CAS Registry Number.

825640-97-9Downstream Products

825640-97-9Relevant academic research and scientific papers

Identification of a crucial amino acid in the helix position 6.51 of human tachykinin neurokinin 1 and 3 receptors contributing to the insurmountable mode of antagonism by dual NK1/NK3 antagonists

Bissantz, Caterina,Bohnert, Claudia,Hoffmann, Torsten,Marcuz, Anne,Schnider, Patrick,Malherbe, Pari

experimental part, p. 5061 - 5076 (2012/09/22)

The neurokinins are neuropeptides that elicit their effect through three GPCRs called NK1, NK2, and NK3. Compounds 5 and 6 are dual hNK1 (Ki of 0.7 and 0.3 nM) and hNK 3 (Ki of 2

DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA

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Page 201, (2008/06/13)

The use of compounds of the general formula wherein the substituents are as described in claim 1 or pharmaceutically active acid-addition salts thereof for the preparation of medicaments for the treatment of schizophrenia.

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