82584-00-7Relevant articles and documents
NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, USE OF THE CATECHOL DERIVATIVE AND USE OF THE PHARMACEUTICAL COMPOSITION
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Page/Page column 17, (2011/04/25)
The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen, lower acyl, lower alkoxycarbonyl or the like; R3 is lower alkyl, halo-lower alkyl, cycloalkyl, heterocycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or the like; R4 is cyano, lower alkoxycarbonyl, carboxy or the like, which exhibit potent COMT inhibitory activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
On the Synthesis of 2,12-Dimethoxy-6,7,8,9-tetrahydro-5H-dibenzazonine-3,11-diol and Other Bridged Biphenyldiols and the E.S.R. of Their Oxidation Products in Relation to the Biosynthesis of Erythrina Alkaloids
Hewgill, Frank R.,Pass, Michael C.
, p. 537 - 554 (2007/10/02)
An improved synthesis in described for the dibenzazonine precursor of erysodienone.Other biphenyl-4,4'-diols, bridged by two, three and five atoms, were also prepared.E.s.r. examination of the oxidation of these compounds produced spectra of the 9,10-dihydrophenanthrene-4,4'-semiquinone system, hitherto unrecorded, but semiquinone spectra could not be obtained from the other diols.
