82607-16-7

Upstream product

• 17434-24-1 2-(4-methoxybenzylidene)-2,3-dihydro-1H-inden-1-one 
• 7421-76-3 2-(4-methoxybenzylidene)indane-1,3-dione 
• 107-91-5 cyanoacetic acid amide 
• 105-56-6 ethyl 2-cyanoacetate 
• 82607-03-2 4-(4-methoxyphenyl)<5H>indeno<1,2-b>pyridine-2(1H)-one 
• 141-97-9 ethyl acetoacetate 
• 60-35-5 acetamide 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant academic research and scientific papers

Highly efficient microwave-assisted solvent free sequential one-pot multicomponent synthesis of novel 2-hydroxy indenopyridin-5-ones and mechanismic computational study

A sequential one-pot three-component microwave-assisted reaction for the efficient and regioselective synthesis of unprecedented polysubstituted 2-hydroxypyridines has been reported. In brief, 1H-indene-1,3(2H)-dione was reacted with acetamide in the presence of NaOH to give N-(1-oxo-1H-inden-3-yl)acetamide, which was treated in situ with aromatic aldehydes to build up the 2-hydroxy-4-aryl-5H-indeno[1,2-b]pyridin-5-ones without using any oxidant and isolation of intermediate.

Synthesis of Heterocycles. Part V. (1) The Synthesis of Substituted Indenopyridines

2-Arylmethylene-1-indanones (1) and 2-arylmethylene-1,3-indanediones (VII) react with active methylene compounds in the presence of ammonium acetate as a basic catalyst to afford substituted pyridines.The postulated routes to the formation of the reported