82613-10-3

Basic information

• Product Name: Ethyl m-ethoxy-p-methoxybenzoylacetate
• CAS NO: 82613-10-3
• Molecular Weight: 266.294
• Mol File: 82613-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethyl m-ethoxy-p-methoxybenzoylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl m-ethoxy-p-methoxybenzoylacetate(82613-10-3)
• EPA Substance Registry System: Ethyl m-ethoxy-p-methoxybenzoylacetate(82613-10-3)

Safety Data

• Hazardous Substances Data: 82613-10-3(Hazardous Substances Data)

Upstream product

• 2651-55-0 3-ethoxy-4-methoxybenzoic acid 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 82613-08-9 3-ethoxy-4-methoxybenzoyl chloride 
• 6100-74-9 3-hydroxy-4-methoxyacetophenone 
• 31526-71-3 3-ethoxy-4-methoxy-acetophenone 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 17892-42-1 O,O-diethylmelannein 
• 82613-11-4 6-Hydroxy-7-methoxy-4-(3'-ethoxy-4'-methoxyphenyl)coumarin 

Relevant articles and documents

An Unambiguous Synthesis of Melannein

Melannein (6-hydroxy-7-methoxy-4-(3'-hydroxy-4'-methoxyphenyl)coumarin, I) and its O,O-diethyl ether (II) have been synthesised.The steps involved in the synthesis of I and II are the respective condensation of o-methoxyhydroquinone with ethyl m-benzyloxy-p-methoxybenzoylacetate (XI) and ethyl m-ethoxy-p-methoxybenzoylacetate (III) in absolute ethyl alcohol in the presence of dry hydrogen chloride gas.The isomeric O,O-diethyl ether of melannein, viz. 6-ethoxy-7-methoxy-4(4'-ethoxy-3'-methoxyphenyl)coumarin (VI) has also been prepared by the condensation of o-methoxyhydroquinone with ethyl p-ethoxy-m-methoxybenzoylacetate (VII).The esters (III), (VII) and (XI) have been prepared by the reaction of the appropriate acetophenone derivatives with diethyl carbonate in the presence of sodium hydride.