2651-55-0

Basic information

• Product Name: 3-ETHOXY-4-METHOXYBENZOIC ACID
• Synonyms: BUTTPARK 52\04-95;AKOS 212-50;3-ETHOXY-4-METHOXYBENZOIC ACID;RARECHEM AL BE 0687;3-ETHOXY-4-METHOXY-BENZOIC ACID 97%
• CAS NO: 2651-55-0
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 2651-55-0.mol

Chemical Properties

• Melting Point: 156-160°C
• Boiling Point: 316.4 °C at 760 mmHg
• Flash Point: 123 °C
• Appearance: /
• Density: 1.178 g/cm³
• Vapor Pressure: 0.000173mmHg at 25°C
• PKA: 4.37±0.10(Predicted)
• CAS DataBase Reference: 3-ETHOXY-4-METHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ETHOXY-4-METHOXYBENZOIC ACID(2651-55-0)
• EPA Substance Registry System: 3-ETHOXY-4-METHOXYBENZOIC ACID(2651-55-0)

Safety Data

• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2651-55-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-Ethoxy-4-methoxybenzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows it to be incorporated into the molecular frameworks of these compounds, potentially enhancing their efficacy and selectivity.
Used in Dye and Pigment Production:
3-ETHOXY-4-METHOXYBENZOIC ACID is utilized in the production of dyes and pigments due to its ability to impart color. Its chemical structure contributes to the color characteristics of the resulting dyes and pigments, making it a valuable component in the formulation of various colorants.
Used in Fragrance and Flavor Manufacturing:
3-Ethoxy-4-methoxybenzoic acid is employed in the creation of fragrances and flavors, where its aromatic properties can be harnessed to develop unique scents and tastes. Its versatility in this application allows for the development of a wide range of products in the fragrance and flavor industries.
Used in Anti-Inflammatory and Antioxidant Research:
3-Ethoxy-4-methoxybenzoic acid has demonstrated potential biological activity and is being researched for its possible use as an anti-inflammatory and antioxidant agent. Its ability to modulate inflammatory responses and combat oxidative stress could make it a promising candidate for therapeutic applications in the future.

InChI:InChI=1/C10H12O4/c1-3-14-9-6-7(10(11)12)4-5-8(9)13-2/h4-6H,3H2,1-2H3,(H,11,12)/p-1

Upstream product

• 1117-96-0 Diazoethan 
• 645-08-9 Isovanillic acid 
• 74-96-4 ethyl bromide 
• 17892-42-1 O,O-diethylmelannein 
• 1131-52-8 3-ethoxy-4-methoxybenzaldehyde 
• 64-67-5 diethyl sulfate 
• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 617-05-0 ethyl vanillate 
• 97966-31-9 3-ethoxy-4-methoxybenzoic acid methyl ester 
• 6702-50-7 3-hydroxy-4-methoxybenzoate 
• 57535-57-6 methyl 3-(benzyloxy)-4-methoxy-benzoate 
• 247569-98-8 ethyl 4-cyclobutylmethoxy-3-methoxybenzoate 
• 3535-24-8 4-ethoxy-3-methoxybenzoic acid methyl ester 

Downstream Products

• 247569-89-7 3-ethoxy-4-methoxy-benzoic acid amide 
• 108439-67-4 3-ethoxy-4-methoxybenzylamine 
• 60758-86-3 3-ethoxy-4-methoxybenzenecarbonitrile 
• 247568-43-0 2-[1-(tert-butoxycarbonyl)-4-piperidinylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-98-9 2-(1-Benzylpiperidin-4-ylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-97-8 2-[1-(Ethoxycarbonyl)piperidin-4-ylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247568-42-9 2-(4-carboxycyclohexylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 

Relevant articles and documents

AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES

The present disclosure provides certain amino acid derivatives that inhibit NF-kB activation and are therefore useful for the treatment of inflammatory diseases. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Provided herein are novel heteroaromatic derivatives, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a prodrug, a pharmaceutically acceptable salt or a prodrug thereof, and pharmaceutical compositions containing such compounds. Also provided herein are uses of such compounds or pharmaceutical compositions thereof in the manufacture of a medicament for treating respiratory diseases, especially chronic obstructive pulmonary disease (COPD).

Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase

Compounds of formula (I) STR1where R 1 is hydrogen; R 2 is nitro, cyano or halo(lower)alkyl; R 3 is phenyl substituted with one or more substituents selected from halogen, cyano and lower alkoxy; A is a lower alkylene group; R 4 is a group CR 6 R 7 R 8 wherein R 6 and R 7 form, together with the carbon atom to which they are attached a cycloalkyl group optionally substituted with hydroxy, lower alkoxy or a lower alkanoylamino; and R 8 is hydrogen; its prodrug and a salt thereof.

Influence of lateral alkoxy substitution on mesomorphic properties of copper complexes

Coordination complexes between copper and some lateral alkoxy chain-substituted N-(4-(4'-alkoxybenzoyloxy)salicylidene)-4-n-butylaniline have been synthesized.The lateral chain was introduced on the outer ring bearing the ester function.In the case of a 3,4-disubstitution, the mesomorphic behavior is related to the number of carbons in the terminal chain.If this is too small, the mesomorphic properties of the complexes disappear.In contrast, copper complexes are liquid crystalline and show more ordered phases by comparison with the free ligand.In case of a 2,4-disubstitution, the phases are nematic and the clearing temperatures are near room temperature, but the observed phases are essentially monotropic for the ligands, as well as for the complexes.Keywords: nematic / copper complex / lateral substitution / Schiff base