82679-60-5Relevant academic research and scientific papers
A convenient one pot asymmetric synthesis of cis-β-lactams: Key precursors for optically active 2-oxaisocephems
Tsubouchi,Tsuji,Yasumura,Tada,Nishitani,Minamikawa,Ishikawa
, p. 441 - 452 (2007/10/02)
Asymmetric annelation of the disilylated imine 3 generated in situ from D-threonine 2 with acid chlorides 4 and triethylamine followed by esterification provided cis-β-lactams 5 and 6 in excellent yields with high diastereoselectivity under mild condition
Stereoregulated synthesis of β-lactams from schiff bases derived from threonine esters
Bose, Ajay K.,Manhas, Maghar S.,Van Der Veen, James M.,Bari, Shamsher S.,Wagle, Dilip R.
, p. 4831 - 4844 (2007/10/02)
A variety of optically active 3-substituted-2-azetidinones has been prepared by the annelation of Schiff bases derived from cinnamaldehyde and D-threonine esters and their absolute configuration determined. When the β-hydroxyl group of threonine is unprot
