827603-03-2Relevant articles and documents
A second-generation total synthesis of (+)-discodermolide: The development of a practical route using solely substrate-based stereocontrol
Paterson, Ian,Delgado, Oscar,Florence, Gordon J.,Lyothier, Isabelle,O'Brien, Matthew,Scott, Jeremy P.,Sereinig, Natascha
, p. 150 - 160 (2007/10/03)
(Chemical Equation Presented). A novel total synthesis of the complex polyketide (+)-discodermolide, a promising anticancer agent of sponge origin, has been completed in 7.8% overall yield over 24 linear steps, with 35 steps altogether. This second-genera