827609-10-9

Basic information

• Product Name: 6H-Cyclopenta[b]thiophen-6-one,4,5-dihydro-5-hydroxy-(9CI)
• Synonyms: 6H-Cyclopenta[b]thiophen-6-one,4,5-dihydro-5-hydroxy-(9CI)
• CAS NO: 827609-10-9
• Molecular Formula: C₇H₆O₂S
• Molecular Weight: 154.18634
• Product Categories: CYCLOPENTANE
• Mol File: 827609-10-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 316.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.519±0.06 g/cm3(Predicted)
• PKA: 12.48±0.20(Predicted)
• CAS DataBase Reference: 6H-Cyclopenta[b]thiophen-6-one,4,5-dihydro-5-hydroxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-Cyclopenta[b]thiophen-6-one,4,5-dihydro-5-hydroxy-(9CI)(827609-10-9)
• EPA Substance Registry System: 6H-Cyclopenta[b]thiophen-6-one,4,5-dihydro-5-hydroxy-(9CI)(827609-10-9)

Safety Data

• Hazardous Substances Data: 827609-10-9(Hazardous Substances Data)

Upstream product

• 1195-52-4 3-(3-thienyl)-2-propenoic acid 
• 16378-06-6 3-(3-thienyl)propanoic acid 
• 5650-52-2 4,5-dihydro-6H-cyclopenta[b]thiophen-6-one 

Downstream Products

• 827609-11-0 (5R,2S)-6-oxo-5,6-dihydro-4H-cyclopenta[b]thien-5-yl 2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate 
• 827609-12-1 (5S,2S)-6-oxo-5,6-dihydro-4H-cyclopenta[b]thien-5-yl 2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate 
• 827609-27-8 N-[(5R,6R)-5-hydroxy-5,6-dihydro-4H-cyclopenta[b]thiophen-6-yl]-2-isopropylbenzenecarboxamide 
• 827609-26-7 N-[(5R,6R)-5-hydroxy-5,6-dihydro-4H-cyclopenta[b]thiophen-6-yl]-2,6-dimethylbenzenecarboxamide 
• 827609-25-6 N-[(5R,6R)-5-hydroxy-5,6-dihydro-4H-cyclopenta[b]thiophen-6-yl]benzenecarboxamide 
• 827609-18-7 (S)-5-hydroxy-4,5-dihydro-6H-cyclopenta[b]thiophen-6-one 
• 827609-16-5 (R)-5-hydroxy-4,5-dihydro-6H-cyclopenta[b]thiophen-6-one 

Relevant articles and documents

Diastereoselective synthesis of thieno[3′,2′:4,5]cyclopenta[1, 2-d][1,3]-oxazolines - New ligands for the copper-catalyzed asymmetric conjugate addition of diethylzinc to enones

Several new ligands featuring a rigid three ring skeleton have been prepared for the first time following a modular approach. Chirality has been introduced by use of an oxazoline moiety fused with a cyclopenta[b]thiophene backbone. The efficiency and stereochemical impact of these ligands on the copper-catalyzed enantioselective addition of Et2Zn to chalcone was examined and enantiomeric excesses up to 79% were achieved using the ligand (R,R)-16 substituted with a methyl group at the cyclopenta moiety. Computational and ESI-mass spectral studies show that these new compounds behave as monodentate ligands towards Cu+. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.