5650-52-2

Basic information

• Product Name: 4,5-Dihydrocyclopenta[b]thiophen-6-one
• Synonyms: 4,5-Dihydrocyclopenta[b]thiophen-6-one;4H-cyclopenta[b]thiophen-6(5H)-one;4,5-dihydro-6H-cyclopenta[b]thiophen-6-one;4H,5H,6H-cyclopenta[b]thiophen-6-one;4H-Cyclopenta[b]thiophen-6(5H)
• CAS NO: 5650-52-2
• Molecular Formula: C₇H₆OS
• Molecular Weight: 138.19
• Product Categories: API intermediates
• Mol File: 5650-52-2.mol
• Article Data: 15

Chemical Properties

• Melting Point: 90-91 °C
• Boiling Point: 239.6°Cat760mmHg
• Flash Point: 98.7°C
• Appearance: /
• Density: 1.322g/cm³
• Vapor Pressure: 0.0398mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,5-Dihydrocyclopenta[b]thiophen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dihydrocyclopenta[b]thiophen-6-one(5650-52-2)
• EPA Substance Registry System: 4,5-Dihydrocyclopenta[b]thiophen-6-one(5650-52-2)

Safety Data

• Hazardous Substances Data: 5650-52-2(Hazardous Substances Data)

Usage

General Description

4,5-Dihydrocyclopenta[b]thiophen-6-one, also known as tetrahydrothiophenone, is a chemical compound with a molecular formula C6H8OS. It is a cyclic ketone with a five-membered ring containing a sulfur atom. 4,5-Dihydrocyclopenta[b]thiophen-6-one is commonly used as a chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Its unique structure and reactivity make it a valuable building block in organic synthesis. Additionally, 4,5-Dihydrocyclopenta[b]thiophen-6-one is also used as a flavoring agent in food products. The compound's diverse range of applications and its ability to easily undergo chemical reactions make it a versatile and important compound in various industries.

InChI:InChI=1/C7H6OS/c8-6-2-1-5-3-4-9-7(5)6/h3-4H,1-2H2

Upstream product

• 26359-23-9 3-thienylpropionic acid chloride 
• 21980-45-0 1-(thiophen-2-yl)-3-(trimethylsilyl)prop-2-yn-1-ol 
• 121792-93-6 2,3-Dibromo-4,5-dihydro-cyclopenta[b]thiophen-6-one 
• 98-03-3 thiophene-2-carbaldehyde 
• 849769-14-8 1-(thiophen-3-yl)-3-(trimethylsilyl)prop-2-yn-1-ol 
• 498-62-4 3-thiophene carboxaldehyde 
• 13191-29-2 thienyl vinyl ketone 
• 40570-64-7 3-chloro-1-(2-thienyl)propan-1-one 
• 189179-83-7 2-(2,5-Dibromo-thiophen-3-ylmethyl)-malonic acid 
• 121792-92-5 3-(2,5-Dibromo-thiophen-3-yl)-propionyl chloride 
• 13191-40-7 3-(2,5-dibromothiophen-3-yl)propionic acid 
• 13191-37-2 2,5-dibromo-3-bromomethylthiophene 
• 121792-91-4 <2,5-Dibrom-3-thenyl>-malonsaeurediethylester 
• 13191-36-1 2,5-dibromo-3-methylthiophene 

Downstream Products

• 827609-10-9 (+/-) 5-hydroxy-4,5-dihydro-6H-cyclopenta[b]thiophen-6-one 
• 960402-67-9 (+/-)-2-(4-chloro-phenyl)-6-[3-methoxy-4-(pyrrolidine-3-carbonyl)-phenyl]-6H-thieno[2,3-c]pyridin-7-one trifluoroacetic acid 
• 960402-65-7 (+/-)-3-{4-[2-(4-chloro-phenyl)-7-oxo-7H-thieno[2,3-c]pyridin-6-yl]-phenylcarbamoyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 960400-59-3 toluene-4-sulfonic acid 2-methoxy-4-[2-(4-methoxy-phenyl)-7-oxo-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl]-phenyl ester 
• 960401-12-1 trifluoromethanesulfonic acid 2-methoxy-4-[2-(4-methoxy-phenyl)-7-oxo-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl]-phenyl ester 
• 960402-73-7 (+/-)-pyrrolidine-3-carboxylic acid {4-[2-(4-chloro-phenyl)-7-oxo-7H-thieno[2,3-c]pyridin-6-yl]-phenyl}-amide 
• 960401-15-4 2-methoxy-4-[2-(4-methoxy-phenyl)-7-oxo-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl]-benzoic acid 
• 960401-13-2 2-methoxy-4-[2-(4-methoxy-phenyl)-7-oxo-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl]-benzoic acid methyl ester 
• 960400-65-1 6-(4-hydroxy-3-methoxy-phenyl)-2-(4-methoxy-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one 
• 960402-40-8 6-(4-bromo-phenyl)-2-(4-chloro-phenyl)-6H-thieno[2,3-c]pyridin-7-one 

Relevant articles and documents

Control of the Bandgap of Conducting Polymers by Rigidification of the ?-Conjugated System

Rigidification of E-1,2(2,2'-dithienylethylene) by bridging the thiophene rings with the central double bond leads to a ca. 0.40 eV decrease of the bandgap of the resulting conducting polymer.

SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE

Compounds having a structure of Formula (IX) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.

Intramolecular Friedel-Crafts Acylation Reaction Promoted by 1,1,1,3,3,3-Hexafluoro-2-propanol

Simple dissolution of an arylalkyl acid chloride in 1,1,1,3,3,3-hexafluoro-2-propanol promotes an intramolecular Friedel-Crafts acylation without additional catalysts or reagents. This reaction is operationally trivial in both execution and product isolation (only requiring concentration followed by purification) and accommodates a broad range of substrates. Preliminary studies that bear upon potential reaction mechanisms are reported.