2-(3-Chlorophenyl)-1-hydrazinecarbothioamide, commonly referred to as CTPhT, is a thioamide derivative with the molecular formula C7H8ClN3S. It is a chemical compound that has demonstrated potential antitumor activity, making it a subject of interest in the field of oncology. CTPhT's mechanism of action includes targeting cellular DNA and inducing apoptosis, which suggests its potential as an effective anticancer agent.
828-11-5
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Basic information
- Product Name: 2-(3-CHLOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE
- Synonyms: 2-(3-CHLOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE;[(3-chlorophenyl)amino]thiourea
- CAS NO:828-11-5
- Molecular Formula: C7H8ClN3S
- Molecular Weight: 201.68
- EINECS: N/A
- Product Categories: N/A
- Mol File: 828-11-5.mol
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Chemical Properties
- Melting Point: 149 °C
- Boiling Point: 316.3±44.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.458±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 11.06±0.70(Predicted)
- CAS DataBase Reference: 2-(3-CHLOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE(CAS DataBase Reference)
- NIST Chemistry Reference: 2-(3-CHLOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE(828-11-5)
- EPA Substance Registry System: 2-(3-CHLOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE(828-11-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 828-11-5(Hazardous Substances Data)
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828-11-5 Usage
Uses
Used in Oncology:CTPhT is used as an anticancer agent for its ability to inhibit the growth of various cancer cell lines in vitro. It is particularly promising due to its potential to combat drug resistance in cancer cells, a significant challenge in cancer treatment.
Used in Cancer Treatment Research:
CTPhT is utilized in research aimed at understanding its mechanism of action, which involves targeting cellular DNA and inducing apoptosis. This research is crucial for developing CTPhT as a therapeutic agent for cancer treatment, with the goal of improving patient outcomes and overcoming resistance issues associated with existing treatments.
Used in Drug Development:
As part of the ongoing exploration of its potential, CTPhT is being investigated for inclusion in drug development programs. Its unique properties and mechanisms suggest that it could be a valuable component in the creation of novel cancer therapies, especially for cancers that have proven difficult to treat with current methods.
Check Digit Verification of cas no
The CAS Registry Mumber 828-11-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,2 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.Calculate Digit Verification of CAS Registry Number 828-11:
(5*8)+(4*2)+(3*8)+(2*1)+(1*1)=75
75 % 10 = 5
So 828-11-5 is a valid CAS Registry Number.
828-11-5Upstream product
828-11-5Downstream Products
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2-(3-CHLOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE
