82803-55-2

Basic information

• Product Name: Dimethyl 3-[(tert-butoxycarbonyl)amino]pentanedioate
• Synonyms: Dimethyl 3-[(tert-butoxycarbonyl)amino]pentanedioate;dimethyl 3-((tert-butoxycarbonyl)amino)pentanedioate(WXC01909)
• CAS NO: 82803-55-2
• Molecular Formula: C₁₂H₂₁NO₆
• Molecular Weight: 275.29824
• Mol File: 82803-55-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 370.9±32.0 °C(Predicted)
• Appearance: /
• Density: 1.117±0.06 g/cm3(Predicted)
• PKA: 10.91±0.46(Predicted)
• CAS DataBase Reference: Dimethyl 3-[(tert-butoxycarbonyl)amino]pentanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyl 3-[(tert-butoxycarbonyl)amino]pentanedioate(82803-55-2)
• EPA Substance Registry System: Dimethyl 3-[(tert-butoxycarbonyl)amino]pentanedioate(82803-55-2)

Safety Data

• Hazardous Substances Data: 82803-55-2(Hazardous Substances Data)

Upstream product

• 63547-62-6 dimethyl 3-aminoglutaconate 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 77313-09-8 3-aminoglutaric acid dimethyl ester 

Downstream Products

• 1117-23-3 3-aminopentane-1,5-diol 

Relevant articles and documents

An efficient enantioselective approach to cyclic β-amino acid derivatives via olefin metathesis reactions

The asymmetric synthesis of polyfunctionalized piperidine- and pyrrolidine-based scaffolds, specifically designed for the preparation of cyclic, conformationally constrained β-amino acids, is realized combining a biocatalytic access to a versatile chiral

COMPOUND HAVING READ-THROUGH ACTIVITY

[Problem] Provision of a novel compound having read-through activity and a drug for the treatment of nonsense mutation-type disease containing this compound. [Solution] A compound represented by the following general formula (1): and a pharmaceutical composition containing this compound.

NOVEL PROCESS FOR THE PREPARATION OF 3-AMINO-PENTAN-1,5-DIOL

The present invention provides a novel method for preparing a key intermediate, 3-amino-pentan-1,5-diol (2), which is useful for the preparation of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidine-7-one (1) a MAP-kinase inhibitor useful in the treatment of rheumatoid arthritis.