828261-38-7Relevant academic research and scientific papers
Synthesis and hybridization affinity of oligodeoxyribonucleotides incorporating 4-N-(N-arylcarbamoyl)deoxycytidine derivatives
Miyata, Kenichi,Tamamushi, Ryuji,Ohkubo, Akihiro,Taguchi, Haruhiko,Seio, Kohji,Sekine, Mitsuo
, p. 9365 - 9368 (2007/10/03)
Modified oligodeoxynucleotides incorporating 4-N-(N-arylcarbamoyl)-dC derivatives 1a-c were synthesized. The 1H NMR spectra of 1a-c suggest that the carbamoyl group forms an intramolecular hydrogen bond with the cytosine ring nitrogen atom so t
Triplex formation by an oligonucleotide containing the novel modified nucleoside 2′-deoxy-N4-phenylcarbamoylcytidine
Guzzo-Pernell, Nancy,Lawlor, John M.,Tregear, Geoffrey W.,Haralambidis, Jim
, p. 965 - 972 (2007/10/03)
2′-Deoxy-N4-phenylcarbamoylcytidine (Pc) was designed for triplex recognition of the cytosine-guanine base pair at physiological pH values to assist in the development of triplex-forming oligomers. Thermal denaturation of a triplex m
