828268-89-9Relevant academic research and scientific papers
Synthesis and glycosidase inhibitory activity of some N-substituted 5a-carba-β-fuco- and β-galactopyranosylamines, and selected derivatives
Ogawa, Seiichiro,Fujieda, Shigeo,Sakata, Yuko,Ishizaki, Masahiro,Hisamatsu, Seiichi,Okazaki, Kensuke,Ooki, Yoriko,Mori, Midori,Itoh, Masayoshi,Korenaga, Takashi
, p. 6569 - 6579 (2007/10/03)
In the course of chemical modification of α-fucosidase inhibitors of 5a-carba-fucopyranosylamine type, an N-dodecyl derivative of the enantiomer 6-deoxy-5a-carba-β-d-galactopyranosylamine demonstrated very strong inhibition of β-galactosidase and β-glucos
Synthesis and glycosidase inhibitory activity of some N-substituted 6-deoxy-5a-carba-β-dl- and L-galactopyranosylamines
Ogawa, Seiichiro,Fujieda, Shigeo,Sakata, Yuko,Ishizaki, Masahiro,Hisamatsu, Seiichi,Okazaki, Kensuke
, p. 3461 - 3463 (2007/10/03)
Chemical modification of 5a-carba-β-DL-fucopyranosylamine (3) generated six N-substituted derivatives 9a-f, among which N-octyl 9b, decyl 9c, and phenylbutyl ones 9f were found to be very strong β-galactosidase as well as β-glucosidase inhibitors. The inh
