82882-71-1 Usage
General Description
L-Histidine, N-[(phenylmethoxy)carbonyl]-1-(triphenylmethyl)-, also known as Boc-L-Histidine, is a compound commonly used in the field of biochemistry and organic synthesis. It is a derivative of the amino acid histidine, which plays a crucial role in the synthesis of proteins and the regulation of physiological processes. The "Boc" group in the compound refers to the tert-butoxycarbonyl protecting group, which is often utilized in peptide synthesis to prevent unwanted side reactions. The compound is commonly used in the production of pharmaceuticals, as well as in the study and development of new drug molecules. Its unique structure and properties make it a valuable tool for researchers and scientists in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 82882-71-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,8 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 82882-71:
(7*8)+(6*2)+(5*8)+(4*8)+(3*2)+(2*7)+(1*1)=161
161 % 10 = 1
So 82882-71-1 is a valid CAS Registry Number.
82882-71-1Relevant articles and documents
IMPROVED METHODS OF OBTAINING Nim-TRITYL-SUBSTITUTED HISTIDINE DERIVATIVES
Pozdnev, V. F.
, p. 322 - 327 (2007/10/02)
Two variants are proposed for the synthesis of Nα-Boc-Nim-tritylhistidiine.The first variant starts from Nα,Nim-di-Boc-histidine, from which the Nim-Boc group is removed with hydrazine hydrate.The Nα-Boc-histidine formed is esterified with chlorotrimethylsilane, tritylated in the imidazole group, and, after the elimination of the trimethylsilyl protection from the carboxyl group, Nα-Boc-Nim-tritylglycine is obtained with a yield of 80percent.The second variant starts from Nα,Nim-ditritylhistidine, which, by treatment with hydrochloric acid in acetone and then with dilute ammonia, is converted into Nim- tritylhistidine.From this, by acylation with di-tert-butyl pyrocarbonate, Nα-Boc-Nim-tritylhistidine is obtained with a yield of 91percent.The acylation of Nim-tritylhistidine with other alkoxycarbonylating reagents leads to Nα-tert-amyl-, Nα-benzyl-, and Nα-4-methoxybenzyloxycarbonyl derivatives of Nim-tritylhistidine.
