829-48-1

Upstream product

• 874-90-8 4-methoxybenzonitrile 
• 75-36-5 acetyl chloride 
• 75-03-6 ethyl iodide 
• 64-17-5 ethanol 

Downstream Products

• 138190-42-8 2-(4-methoxy-phenyl)-5-(1-methyl-butylidene)-3,5-dihydro-imidazol-4-one 
• 138190-43-9 5-(4-methoxy-cyclohexyLiDene)-2-(4-methoxy-phenyl)-3,5-dihydro-imidazol-4-one 
• 2564-57-0 4-carbomethoxy-2-(4-methoxyphenyl)-δ²-thiazoline 
• 10602-66-1 O-ethyl 4-methoxythiobenzoate 
• 92666-91-6 2-[6,7-Dimethoxy-2-(4-methoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-acetamide 
• 159053-06-2 5-(4-methoxylphenyl)-3-(2-pyrazinyl)-1H-1,2,4-triazole 
• 935750-39-3 1,2-bis(4-methoxyphenyl)-2-imidazoline 
• 6926-51-8 5-(4-methoxyphenyl)-1H-tetrazole 
• 86843-96-1 2-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridine 

Relevant academic research and scientific papers

Synthesis of Highly Fused Pyrano[2,3- b]pyridines via Rh(III)-Catalyzed C-H Activation and Intramolecular Cascade Annulation under Room Temperature

A facile access to the polycyclic-fused pyrano[2,3-b]pyridines has been established under room temperature via Rh(III)-catalyzed C-H bond activation and intramolecular cascade annulation. This strategy features high efficiency, unique versatility, and gen

Benzimidates as gem-Diamidation and Amidoindolyzation Cascade Synthons with a Hydrated NiII Catalyst

We contributed a new benzimidate chemistry through moisture-insensitive NiII/NiII-FeIII combo-catalysis for a simultaneous 2-3 bond-forming gem-diamidation and amidoindolyzation cascade reaction to construct symmetrical an

An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds

Herein, we describe the development of a simple, high yielding and stereocontrolled strategy for the synthesis of a series of triazolopiperazines and other biologically relevant fused scaffolds from optically active amino acids. This route was applied to the synthesis of 22 scaffolds containing new, previously inaccessible vectors and used to access a novel analogue of ganaplacide.

Rh(III)-Catalyzed [3 + 2] Annulation via C-H Activation: Direct Access to Trifluoromethyl-Substituted Indenamines and Aminoindanes

The rhodium(III)-catalyzed direct C-H addition and annulation of benzimidates and aldimines with β-(trifluoromethyl)-α,β-unsaturated ketones is described. This protocol provides the facile and efficient formation of various trifluoromethyl-containing inde

Rhodium-Catalyzed Relay Carbenoid Functionalization of Aromatic C-H Bonds toward Fused Heteroarenes

A rhodium-catalyzed annulation between ethyl benzimidates and α- aroyl sulfur ylides was developed, affording a series of pyrano[4,3,2-ij]isoquinoline derivatives in moderate to good yields with good functional group compatibility. The procedure featured

Synthesis of Isoquinolines through IrIII-Catalyzed C–H Activation/Annulation from Benzimidates with Hydroxylisopropylalkynes

An IrIII-catalyzed cascade reaction consisting of C–H activation/annulation of benzimidates with hydroxylisopropylalkynes is reported. A broad range of isoquinolines has been prepared in one step with good functiona-group tolerance and high eff

Controllable Rh(III)-Catalyzed C-H Arylation and Dealcoholization: Access to Biphenyl-2-carbonitriles and Biphenyl-2-carbimidates

A controllable Rh(III)-catalyzed C-H arylation and dealcoholization of benzimidates with arylboronic esters was developed, delivering various biphenyl-2-carbonitriles and biphenyl-2-carbimidates by simply tuning the reaction conditions. This approach features high efficiency, good functional group tolerance, and easy operation. It also provides an alternative pathway to thoroughly exploit the directing group in transition-metal-catalyzed C-H activations.

Ruthenium (II)-Catalyzed Oxidant-Free Coupling/Cyclization of Benzimidates and Sulfoxonium Ylides to Form Substituted Isoquinolines

A ruthenium-catalyzed direct mono-C?H functionalization/annulation cascade reaction of benzimidates and sulfoxonium ylides has been developed. The reaction proceeds smoothly with a broad range of substrates, giving access to a variety of isoquinoline deri

Synthesis of Functionalized Indenones via Rh-Catalyzed C-H Activation Cascade Reaction

An efficient and expeditious protocol for the synthesis of diverse difunctionalized indenones through rhodium-catalyzed C-H activation and multistep cascade reaction of benzimidates and alkenes has been developed. The transformation involves the cleavage and formation of multiple bonds in one pot under mild reaction conditions, and Mn(OAc)2 plays an important role in the reaction.

Cobalt-Catalyzed Oxidant-Free Spirocycle Synthesis by Liberation of Hydrogen

The first example of oxidant-free cobalt-catalyzed synthesis of five-membered spirocycles is reported from benzimidates and maleimides utilizing nitrobenzene as promoter. In contrast to previously known cobalt-catalyzed oxidative C-H functionalization rea