83004-37-9

Upstream product

• 64416-13-3 1,1,1-trifluoro-2,2-bis-(4-nitrophenyl) ethane 
• 2372-45-4 sodium butanolate 
• 64416-14-4 1,1,1-trifluoro-2-⁽²⁾H-2,2-di(4-nitrophenyl)ethane 
• 340-04-5 1-phenyl-2,2,2-trifluoromethylethanol 
• 636-98-6 p-nitrobenzene iodide 
• 1256278-61-1 2,2-difluoro-1-tributylstannylethenyl p-toluenesulfonate 
• 24067-17-2 4-nitrophenylboronic acid 
• 384-94-1 1,1'-(2,2,2-trifluoro-1,1-ethanediyl)dibenzene 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 127087-57-4 sodium sec-butoxide 
• 139-02-6 sodium phenoxide 
• 683-60-3 sodium isopropylate 
• 141-52-6 sodium ethanolate 
• 6819-41-6 sodium n-propoxide 

Downstream Products

• 64416-13-3 1,1,1-trifluoro-2,2-bis-(4-nitrophenyl) ethane 
• 96694-65-4 2,2-di(4-nitrophenyl)-1-fluoro-1-isopropoxy-ethene 
• 96694-62-1 2,2-di(4-nitrophenyl)-1-fluoro-1-ethoxy-ethene 
• 83004-42-6 2,2-di(4-nitrophenyl)-1-fluoro-1-methoxy-ethene 

Relevant academic research and scientific papers

Consecutive cross-coupling reactions of 2,2-difluoro-1-iodoethenyl tosylate with boronic acids: Efficient synthesis of 1,1-diaryl-2,2-difluoroethenes

The cross-coupling reactions of 2,2-difluoro-1-iodoethenyl tosylate (2) with 2 equiv of boronic acids in the presence of catalytic amounts of Pd(OAc)2 and Na2CO3 afforded the mono-coupled products 3 and 5 in high yields. The use of 4 equiv of boronic acid

Preparation of (2,2-difluoroethenylidene)bis(tributylstannane) and arylation reaction: Efficient approach to 1,1-diaryl-2,2-difluoroethenes

Reaction of 2,2-difluoro-1-tributylstannylethenyl p-toluenesulfonate (1) with bis(tributyltin) in the presence of 5 mol % Pd(PPh3)4 and 30 equiv LiBr in THF at reflux temperature for 7 h afforded (2,2-difluoroethenylidene)bis(tributylstannane) (2) in a 70% yield. Coupling reaction of 2 with aryl iodides in the presence of 5 mol % Pd(PPh 3)4 and 5 mol % CuI in DMF at 80 °C for 3-4 h provided the coupled products 3 in 59-85% yields.

Kinetics and mechanism of the dehydrohalogenation of Ar2CHCX3 and Ar2CHCHX2 by strong N-bases

The kinetics and mechanism of the elimination reactions of 1,1,1- trifluoro-, 1,1,1-trichloro-, 1,1,1-tribromo-, 1,1-dichloro- and 1,1-dibromo- 2,2-bis(4-nitrophenyl)ethanes and two strong N-bases: 1,5,7- triazabicyclo[4.4.0]dec-5-ene (TBD) and 7-methyl-1

CARBANIONS IN E1cB ELIMINATION AND ADDITION REACTIONS

Visible absorption spectra of the reaction products of di(4-nitrophenyl)methanes derivatives with bases promoted by macrocyclic compounds, are discussed.The kinetic and equilibrium measurements are reported for the reactions: 1,1,1-trifluoro-2,2-di(4-nitr

REACTIVITY OF FREE IONS AND ION PAIRS OF ALKOXIDE BASES IN E1cB ELIMINATION REACTIONS. INFLUENCE OF CROWN ETHERS AND CRYPTANDS

Rate constans and deuterium kinetic isotope effects for free ions and ion pairs of lithium, sodium, potassium ethoxide and propoxidebases for the elimination of HF from 1,1,1-trifluoro-2,2-di(4-nitrophenyl)ethane (Ar2CHCF3) have been calculated.The result

KINETICS, ISOTOPE EFFECTS AND MECHANISM OF THE REACTION OF SOME DINITROPHENYLETHANES WITH SODIUM PROPANETHIOLATE IN PROPANOL

The reaction between Ar2CHCF3, Ar2CHCCl3, Ar2CHCHCl2 (where Ar=O2NC6H4) and sodium propanethiolate in propanol has been investigated.The reaction of Ar2CHCF3 with sodium propanethiolate gave the following alkenes: Ar2C=CF2, Ar2C=CF(SPr) and Ar2C=C(SPr)2,

KINETICS, MECHANISM AND DEUTERIUM ISOTOPE EFFECT OF THE REACTION OF 1,1,1-TRIFLUORO-2,2-DI(4-NITROPHENYL)ETHANE WITH SODIUM PHENOLATE IN ALCOHOLS. INFLUENCE OF CROWN ETHERS AND CRYPTANDS

The reaction of 1,1,1-trifluoro-2,2-di(4-nitrophenyl)ethane with sodium phenolate in ethanol, n-propanol, iso-propanol, n-butanol, sec-butanol and t-butanol has been investigated. 1-Fluoro-1-phenoxy-2,2-di(4-nitrophenyl)ethane formed from the intermediate

Nucleophilic attack on the carbon-carbon double bond. I. Reaction of primary and secondary amines with 2,2-di(4-nitrophenyl)-1,1-difluoroethene

The reaction of primary and secondary amines with 2,2-di(4-nitrophenyl)-1,1-difluoroethene (1) in acetonitrile solvent gives first 2,2-di(4-nitrophenyl)-1-fluoro-1-aminoethene (2) and then 2,2-di(4-nitrophenyl)-1,1-difluoro-1-aminoethane (3).With excess a

The kinetics, isotope effects, and mechanism of the reaction of 2,2-di(4-nitrophenyl)-1,1,1-trifluoroethane with alkoxide bases in alcohol solvents

The reaction between 2,2-di(4-nitrophenyl)-1,1,1-trifluoroethane and the alkoxide bases O-CH3, O-C2H5, O-nC4H9, O-CH(CH3)2 and O-C(CH3)3 in their corresponding alcohol solvents is a multistep reaction

The reinvestigation of the kinetics of the reactions of fluorodi(4-nitrophenyl)ethanes with sodium methoxide in methanol

The procedure previously described for the preparation of 1-fluoro-2,2-di(4-nitrophenyl)ethane actually yields 1,1,2-tri(4-nitrophenyl)ethane.Fluoro-2,2-di(4-nitrophenyl)ethane has been prepared and rate constants, isotope effects, and activation parameters for the β-elimination reaction with methoxide ion in methanol are reported.These parameters indicate a concerted E2 mechanism, with a fairly symmetrical transition state.The subsequent dimerization reaction of the olefin product to yield 1,1,3,3-tetra(4-nitrophenyl)butene-1 is described.The reaction of 1,1,1-trifluoro-2,2-di(4-nitrophenyl)ethane with methoxide ion in methanol has been reinvestigated and the reaction on the first product 1,1-difluoro-2,2-di(4-nitrophenyl)ethylene with excess methoxide, to give di(4-nitrophenyl)ketene dimethylacetal in a multistep reaction, is reported.