83015-28-5

Usage

Uses

Used in Organic Chemistry:
1-BROMO-2-(1,1,2,2-TETRAFLUOROETHOXY)BENZENE is used as a reagent in bromination reactions for the synthesis of various organic compounds. The presence of the bromine atom allows for the formation of new chemical bonds and the modification of existing ones, making it a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Fluorochemical Industry:
1-BROMO-2-(1,1,2,2-TETRAFLUOROETHOXY)BENZENE is used as a building block in the synthesis of fluorinated compounds. The tetrafluoroethoxy group in the molecule can be further modified or used as a precursor for the development of new fluorochemicals with unique properties. These fluorinated compounds may find applications in various industries, such as refrigerants, lubricants, and materials with specific chemical or physical properties.
Used in Environmental Remediation:
1-BROMO-2-(1,1,2,2-TETRAFLUOROETHOXY)BENZENE may be used as a component in the development of new technologies for environmental remediation. Its unique structure and reactivity could potentially be utilized in the degradation of pollutants or the capture of harmful substances, contributing to cleaner and more sustainable processes.

Upstream product

• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 108-95-2 phenol 
• 100-67-4 potassium phenolate 
• 139-02-6 sodium phenoxide 

Downstream Products

• 934585-95-2 2-phenoxytetrafluoroethane-1-sulfinic acid 

Relevant academic research and scientific papers

Synthesis and Reactivity of Fluoroalkyl Copper Complexes by the Oxycupration of Tetrafluoroethylene

The copper(I)-mediated generation of -OCF2CF2- moieties by the oxycupration of tetrafluoroethylene (TFE) using either copper aryloxides or alkoxides is disclosed. The key intermediates, 2-aryloxy-1,1,2,2-tetrafluoroethyl and 2-alkoxy

Visible-light-induced installation of oxyfluoroalkyl groups

(Hetero)aryloxytetrafluoroethylation of heteroaromatics and alkenes has been achieved by visible-light photocatalysis utilizing readily synthesized oxyfluoroalkyl reagents. The mild reaction conditions and the high diversity on both substrates and oxyfluoroalkyl reagents make this a useful method for late-stage modifications in the development of various functional molecules.

Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species

We have made a systematic investigation on the copper(0)-mediated tetrafluoroethylenation of iodobenzene with structurally diverse 2-bromo-1,1,2,2-tetrafluoroethyl compounds. A comparison of this reaction with 1,2,2-trifluoro-1-phenylethylation and the known functionalized difluoroalkylation demonstrates that the substituent R of α,α-difluoroalkyl copper species RCF2Cu plays a crucial role on their reactivity, which is believed to be useful for the development of new fluoroalkylation reactions under the promotion of transition metals.

A novel semi-fluorinated graft copolymer containing perfluorocyclobutyl aryl ether-based backbone

The synthesis of a series of novel semi-fluorinated graft copolymers bearing perfluorocyclobutyl (PFCB) aryl ether-based backbone and polystyrene side chains is described. This work initially focused on the synthesis of a trifluorovinyl ether (TFVE) monomer containing a bromine atom, which could be employed as an initiating site for atom transfer radical polymerization (ATRP). Thermal cyclopolymerization of this TFVE monomer provided a macromolecular initiator followed by subsequent initiating ATRP of styrene to afford the desired PFCB aryl ether-based graft copolymers.

A practical synthesis of aryl tetrafluoroethyl ethers via the improved reaction of phenols with 1,2-dibromotetrafluoroethane

An efficient and practical synthesis of various aryl tetrafluoroethyl ethers by the reaction of phenols with 1,2-dibromotetrafluoroethane and the subsequent reduction with zinc dust was described. The nucleophilic substitution of 1,2-dibromotetrafluoroethane with phenols initiated by bromophilic attack was improved by using Cs2CO3 as a base and DMSO as a solvent.

Sub-50 nm feature sizes using positive tone molecular glass resists for EUV lithography

Extreme ultra violet (EUV) lithography is one of the most promising next generation lithographic techniques for the production of sub-50 nm feature sizes with applications in the semiconductor industry. Coupling this technique with molecular glass resists

Synthesis and characterization of a novel perfluorocyclobutyl aromatic ether-based ABA triblock copolymer

A novel perfluorocyclobutyl aromatic ether-based ABA triblock copolymer (A: polystyrene block; B: perfluorocyclobutyl aromatic ether-based fluoropolymer block) was synthesized by combination of atom transfer radical polymerization (ATRP) of styrene and th

Aromatic monomers with pendant fluoroalkylsulfonate and sulfonimide groups

Novel styrene and dimethylisophthalate monomers with pendant lithium fluoroalkylsulfonate or sulfonimide functional groups have been prepared from the corresponding phenolic intermediates. One route involves several steps and uses 1,2-dibromotetrafluoroethane as the key fluorinated intermediate. A second route with fewer steps utilizes a perfluoroalkylsulfonyl-substituted vinyl ether as the source of the fluorinated substituents but affords a product with significantly higher equivalent weight.

SPONTANEOUS REACTIONS OF POTASSIUM PHENOXIDE WITH DIBROMOPERFLUOROALKANES. FIRST EVIDENCE FOR BROMOPHILIC ATTACK ON C-Br BONDS BY THE PHENOXIDE ION.

In contrast to earlier reports, It has been found that dibromoperfluoroalkanes actually can react spontaneously with PhOK, yielding fluoroalkyl phenyl ethers as products.Evidence for an anionic chain mechanism involving a bromophilic attack by the phenoxyde ion is presented.

CONDENSATION OF 1,2-DIBROMOTETRAFLUOROETHANE WITH VARIOUS POTASSIUM THIOPHENOXIDES AND PHENOXIDES

BrCF2CF2Br reacts easily with various potassium thiophenoxides and phenoxides to give respectively 2-bromo tetrafluoroethyl thioethers and ethers.The lipophilicity of C6H5SCF2CF2Br and C6H5OCF2CF2Br is measured and compared with that of the well known C6H5SCF2CF2H and C6H5OCF2CF2H.