830358-48-0

Usage

General Description

2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-[2-(3-methoxyphenyl)ethyl]- is a chemical compound with the molecular formula C15H14N2O4. It is a pyrimidinetrione derivative in which the pyrimidine ring has oxygens at positions 2, 4, and 6, and is substituted by a 1-[2-(3-methoxyphenyl)ethyl] group. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-[2-(3-methoxyphenyl)ethyl]- is commonly used in the pharmaceutical industry as an active ingredient in medications for the treatment of various conditions. It may also have applications in research and development for its potential medicinal properties.

Upstream product

• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 69226-63-7 [2-(3-methoxy-phenyl)-ethyl]-urea 
• 105-53-3 diethyl malonate 

Downstream Products

• 1369252-34-5 5-((9-methoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)oxy)-2-(3-(trifluoromethyl)phenoxy)benzonitrile 
• 1369252-36-7 2-{[(2-chloro-4-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}phenyl)methyl]oxy}-9-(methyloxy)-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one 
• 1369252-77-6 2-((5-chloropyridin-3-yl)oxy)-5-(((9-methoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)amino)methyl)benzonitrile 
• 1369252-78-7 2-((4-((5-chloropyridin-3-yl)oxy)benzyl)amino)-9-methoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one 
• 1369252-89-0 5-({[9-(methyloxy)-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl]oxy}methyl)-2-{[6-(trifluoromethyl)-3-pyridinyl]oxy}benzonitrile 
• 1369252-92-5 9-methoxy-2-((4-(3-(trifluoromethyl)phenoxy)benzyl)oxy)-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one 
• 1369252-93-6 2-((3,5-difluoro-4-(3-(trifluoromethyl)phenoxy)benzyl)amino)-9-methoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one 
• 1369253-00-8 5-(2-cyano-4-(((9-methoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)(methyl)amino)methyl)phenoxy)nicotinonitrile 

Relevant academic research and scientific papers

NOVEL DIHYDROPYRIMIDINOISOQUINOLINONES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS.

A compound according to Formula Ia: wherein L1, G, and R1 are as described herein. The present invention relates to novel compounds according to Formula I that antagonize GPR84, a G-protein-coupled receptor that is involved in inflam

TRICYCLIC COMPOUNDS, PREPARATION METHODS, AND THEIR USES

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.