830358-75-3Relevant academic research and scientific papers
Synthesis and antiviral and cytostatic evaluations of the new c-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4′,5′-didehydro-L- ascorbic acid derivatives
Gazivoda, Tatjana,?ok?evi?, Mario,Kralj, Marijeta,?uman, Lidija,Paveli?, Kre?imir,De Clercq, Erik,Andrei, Graciela,Snoeck, Robert,Balzarini, Jan,Mintas, Mladen,Rai?-Mali?, Silvana
, p. 4105 - 4112 (2007)
The novel C-5 alkynyl substituted pyrimidine (1-11) and furo[2,3-d]pyrimidine derivatives (12-22) of L-ascorbic acid were synthesized by coupling of 5-iodouracil-4′,5′-didehydro-5′,6′-dideoxy- L-ascorbic acid with terminal alkynes by using Sonogashira cro
Novel pyrimidine and purine derivatives of L-ascorbic acid: Synthesis and biological evaluation
Rai?-Mali?, Silvana,Hergold-Brundi?, Antonija,Nagl, Ante,Grdi?a, Mira,Paveli?, Kre?imir,De Clercq, Erik,Mintas, Mladen
, p. 2673 - 2678 (2007/10/03)
The novel pyrimidine derivatives 1-6 of 2,3-dibenzyl-4,5-didehydro-5,6- dideoxy-L-ascorbic acid were synthesized by the condensation of pyrimidine bases with 5,6-diacetyl-2,3-dibenzyl-L-ascorbic acid (DDA). Both N-9 (7) and N-7 (8) regioisomers were obtai
