83038-71-5

Upstream product

• 22746-83-4 4-benzylbenzoyl chloride 
• 620-86-0 4-Benzylbenzoic acid 
• 57-88-5 cholesterol 
• 134-84-9 4-Methylbenzophenone 
• 100-53-8 phenylmethanethiol 
• 943868-13-1 4-benzylsulfanyl-2,3,5,6-tetrafluoropyridine 
• 28144-70-9 anthranilic acid amide 
• 611-95-0 4-carboxybenzophenone 

Relevant academic research and scientific papers

Aromatization as an Impetus to Harness Ketones for Metallaphotoredox-Catalyzed Benzoylation/Benzylation of (Hetero)arenes

Herein we report ketones as feedstock materials in radical cross-coupling reactions under Ni/photoredox dual catalysis. In this approach, simple condensation first converts ketones into prearomatic intermediates that then act as activated radical sources for cross-coupling with aryl halides. Our strategy enables the direct benzylation/benzoylation of (hetero)arenes under mild reaction conditions with high functional group tolerance.

Desulfurative Ni-Catalyzed Reductive Cross-Coupling of Benzyl Mercaptans/Mercaptoacetates with Aryl Halides

The C-S activation and sulfur removal from native thiols is challenging, which limits their application as feedstock materials in organic synthesis despite their natural abundance. Herein, we introduce a per-/polyfluoroaryl moiety, which serves as a redox-active scaffold, into sp3-hybridized thiols to activate the C-S bond. Using a Ni catalyst with MgBr2 as an additive, the S group can be removed to yield an aliphatic radical that can react with an aryl halide in a reductive cross-coupling.

Thermal Properties of Cholesteryl and β-Sitosteryl Esters: The Effect of the Rigid Core on the Thermal Stabilities of Cholesteric and Smectic A Phases

The effect of a central linkage X on the thermal stabilities of the cholesteric and smectic A phases of cholesteryl and β-sitosteryl esters of 4-aryl-X-benzoic and 4-aryl-X-cyclohexanecarboxylic acids (X=-COO-, -CH=N-, -N=N-, -CO-, etc.) has been examined.In both series, the cholesteric-isotropic and smectic A-cholesteric transition temperatures and the transition enthalpies are discussed in terms of the molecular structures and also the angular correlation parameter J22 of the carboxy functions.The transition enthalpies for the smectic A-cholesteric transition are also discussed in terms of the McMillan theory.

Liquid Crystalline Properties of Cholesteryl ω-Arylalkanoates

The thermal properties of the homologous series of cholesteryl ω-(4-benzoylphenyl)- (I), ω-(4-benzylphenyl)- (II), ω-benzoyl- (III), and ω-phenoxyalkanoate (IV) have been investigated.For series I and II the cholesteric-isotropic (Ch-I) transition temperatures, enthalpies, and entropies show a remarkable alternation.For series III and IV, the transition temperatures, enthalpies, and entropies exhibit weak alternation and their trends are opposite to those for series I and II, and the cholesteryl ω-phenylalkanoates.The cholesteric-isotropic transition temperatures are discussed in terms of the geometrical and electrical alternations stemming from the terminal aryl groups, and also the relative importance between these two terms.

Effect of Chain Length on Mesomorphism of Steroid Esters of 4-(4-Alkylphenyl-X)benzoic Acids with X = CO, O, S, and CH2

To examine the effect of bent shapes on mesomorphic properties a homologous series of steroid esters have been prepared: H(CH2)n-4-C6H4-X-4-C6H4COOR, X = CO, O, S, CH2, R = cholesteryl, β-sitosteryl, cholestanyl, stigmasteryl, ergosteryl; n = 0-15.The chain elongation results in an increase in not only the molecular length but also the breadth due to the angular linkage, X.The steroid portions are of primary importance for the mesomorphic properties of the present series, and the thermal stability of the mesophases is strongly dependent on the mesogenic power of the aryl portions, where the effective order is CO > O > S > CH2.The transition enthalpies and entropies for the smectic A-cholesteric and cholesteric-isotropic (Ch-I) transitions are almost independent of the chain length of the alkyl group, indicating that a long alkyl chain has no role from a thermodynamical piont of view.Within the mesophases, the aryl and steroid cores are assumed to be piled up, interacting with each other, and the alkyl groups are apart from each other to avoid short-range interaction.

INFLUENCE OF THE ANGULAR LINKAGE ON THE MESOMORPHIC PROPERTIES OF CHOLESTERYL ARYLBENZOATES.

Some cholesteryl esters of arylbenzoic acids incorporating angular linkage such as -Co-, -O-, -S-, and -CH//2-, were prepared, and the transition temperatures and heats determined. The cholesteric-isotropic transition temperatures are likely to correlate with the angular correlation parameters of these carboxylic acid moieties. The mesomorphic phenomena are discussed in terms of the molecular structure and electronic effect of these linkages.