83113-91-1Relevant academic research and scientific papers
Optical Resolution of 2-(Anilinomethyl)pyrrolidine
Saigo, Kazuhiko,Tanaka, Jun,Nohira, Hiroyuki
, p. 2299 - 2300 (1982)
(+/-)-2-(Anilinomethyl)pyrrolidine, prepared from (+/-)-5-oxopyrrolidine-2-carboxylic acid, was effectively resolved into a pair of enantiomers by fractional crystallization of its mandelic acid salt.Moreover, the preferential crystallization of its p-hydroxybenzoic acid saly was found to give both enantiomers in high optical purities by alternate seeding.
Novel indole derivative and medicine containing the same (by machine translation)
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Paragraph 0248; 0252, (2018/06/30)
[A] formation of Amyloid fibrils can be compounds, including therapeutic or prophylactic agent for neurodegenerative disease Amyloid fibrils formation inhibitor compound and of. (I) or its pharmaceutically acceptable compound represented by the formula [a] or a salt or solvate thereof includes the, Amyloid fibrils formation inhibitor. [R1 And R2 Each independently is H, an alkyl group, a cyano group or the like; R3 And R4 Each independently is H, or an alkyl group; R3 And R4 The, joint may form a ring; Ar1 And Ar2 The substituted or unsubstituted heteroaryl group are independently substituted/unsubstituted aryl groups /; X and Y are each independently a single bond, - (=O) - C etc., Z is O or CH2 ; N is an integer of 1 - 3][Drawing] no (by machine translation)
